November 2025

Contents

Journal scan

• Importance of rapid PEP: predicting impact of delay and duration of 2- and 3-drug PEP

• Case of functional cure reported in an elite controller after 22 years without ART

• Lenacapavir drug resistance: rapid switching and the need for resistance testing

• Australian survey reports limited interest in CAB-LA PrEP by gay and bisexual men

Early access

• The international impact of US policies on HIV: news from AVAC’s Global Health Watch

• UNAIDS calls for continued global solidarity, funding, human rights and community leadership to overcome the 2025 funding crisis

Special reports

• America First global strategy: Does rapid withdrawal jeopardise pledge to Global Fund?

Conference reports

• Sleep disorders and quality of sleep added to EACS management guidelines

Treatment access

• Anti-vaccine propaganda added to US CDC website

• Global Fund announces $11.3 billion in pledges for 8th round of funding: still $7 billion short