Question
Will multivitamins risk PEP not working?
1 April 2023. Related: All topics, Drug interactions.
I’ve been using multivitamins for years, now I’m on PEP and I’ve suspended its use since day 2 of PEP (day 1 I ingested the multivitamin 8-10h before, before I had my high risk exposure).
The fact that I used them for years and used them on day 1 can compromise the efficacy of my PEP treatment? I’m desperate!
My PEP regimen is Dolutegravir, Lamivudine and Tenofovir.
Answer
Hi, how are you doing?
Having been taking multivitamins for years it will not risk reducing how effective PEP is.
As on the first day your multivitamins were taken 10 hours before, there is no risk of interaction.
You can continue taking multivitamins for the duration of PEP. Taking them at the opposite end of the day to when you take PEP will prevent any risk of interaction.
This means PEP will remain effective.
Josh.
Hello Paul and thanks for getting in touch.
Please don’t worry about that first dose, I am sure there is nothing to worry about
Avoid the multivitamins for the time you are on PEP though just to be on the safe side.
Hi,
I’ve taken my multivitamins and after 2hours I started my 1st PEP to start 49hours early on 72hours window period on PEP
Will this affect the effectiveness of PEP?
Hello Paul and thanks for getting in touch.
Please don’t worry about that first dose, I am sure there is nothing to worry about
Avoid the multivitamins for the time you are on PEP though just to be on the safe side.
Hi, I’ve taken my multi-vitamins and after 2 hours of taking it I started on PEP for my 1st dose (so I can start on the treatment within less than 72hours)
Will this affect the effectiveness of PEP?