Q and A

Question

Does TLD cause lipodystrophy?

Does TLD affects the fat distribution on the body or does it causes lipodystrophy?

Answer

Hi, how are you doing?

No. TLD does not cause lipodystrophy.

Lipodystrophy is a symptom associated with older HIV medications like stavudine and zidovudine. This is not associated with TLD.

TLD in some people can cause weight gain of around 10% of their body weight in the first 2 years. This has been linked with an increased appetite.

In fewer people, it has been noted that weight loss can occur but this is rare and is different to lipodystrophy.

The changes in weight that happen on TLD can be managed with diet and exercise. Lipodystrophy cannot be managed in this way and require changing treatments and is not always reversible.

Josh.

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