Question
Is there an interaction between Acyclovir and TLD?
24 November 2023. Related: All topics, Drug interactions.
Hi I-base, is there any interaction between TLD and Acyclovir?
Answer
Hi, how are you doing?
There is some risk of interaction between Acyclovir and tenofovir.
Both of these drugs are eliminated from the body by the kidneys. Because they are both eliminated in the same way, the drugs will compete to be excreted leading to potentially elevated levels of drug in the body for a longer amount of time as the kidney cannot handle eliminating both at the same time.
This risks increasing the likelihood of tonofovirs kidney damaging effects. For this reason it is recommended that you speak with your doctor first before taking these two medications together. It may require that you have kidney function tests, or a different drug other than acyclovir is offered.
Josh.
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