Question
Is it ok if I take my meds 15 or 30 mins late?
10 October 2016. Related: Adherence, All topics.
Do you have to take your arvs at exactly the same time each day? Will for example 30 mins (or even an hour) each way have any impact whatsoever on the suppression of the virus or cause resistance? I am worried as even though I take them every day some days it is 15 or 30 mins later or earlier than the previous day.
Answer
Thank you for your question.
It is sometimes difficult to take your meds at the exact same time everyday.
Even when starting, there is a window of about an hour either side of your target time when it is still fine to take them.
For example, if you want to take your meds every night at 10 pm, then any time between 9pm and 11pm will be fine.
Everyone has a few times when we forget our meds though.
The less this happens the better. But if it does happen once in a while then there is nothing to worry about. If you forget in the future, take them as soon as you remember. However, if this is already close to the next dose DO NOT take a double dose.
Once you get an undetectable viral load, especially if it has been undetectable for several years, you have more flexibility. This partly depends on which drugs you are using.
Some once daily drugs (including tenofovir DF, emtricitabine and efavirinz) have long half-lives. This means drug levels stay in your body for long enough to cover being several hours late or even missing a dose completely.
Several studies are looking at whether reduced dosing might be safe – for example by only taking ART for four days a week. We need bigger studies before we know if this is safe though.
Note: this question was updated in October 2016 from and original answer in April 2011.
Hi Jake,
This is fine. As Simon says above, you have a window of about an hour either side of 10-10:10pm. If forgetting to take your meds on time happens just occasionally like this it’s fine. But it’s best not to be late a lot of the time.
Hi I am taking 3in1 (efavirenz, lamivudine, tenofovir) every night at 10-10:10pm. But tonight i took it past 11pm aroun 11:15pm. I forgot because i went to our neighbor to fix something. But i wasn’t planning on changing time. This just happened just now.
Hi Ram,
I’m not sure about your question. Are you planning to change the time you take it?
Please let us know what HIV meds you’re on. And do you have access to your CD4 count and viral load results?
what if i take my medicine 8 o clock in the morning
Hi Dee,
Its OK to take your meds a few hours either side of your normal time. This won’t be an issue.
hi
took Anonza”ART” 3HOURS later than my normal time. this happens thrice a month max.
what are the effects ?
Hi Johanna,
Yes you’ll be fine. As it says on this Q&A you have a window of about an hour either side of your regular target time of 10 pm.
Atroiza drug levels stay in your body for long enough to cover being several hours late.
Hy I took my atroiza at 10pm so last night I felt sleepy and took them on past 11 pm is it fine
Hi Sbu,
Its perfectly fine to take your meds a few hour either side of your normal time, this isn’t an issue.
Hello, I take my ARVs(FTC) at 10pm, but usually when I am sleepy I take them at anytime between 9PM – 10PM, is there a ny risk in doing this?