Question

Will taking PrEP late work with on demand dosing?

27 April 2020. Related: All topics, PrEP.

Hi, I take PrEP with on demand dosing and after having sex after my first double dose i remembered my first dose post sex on time. However, my second dose was 5h late and 3rd dose was 5h late too. Will this affect my level of protection and should i continue taking it 5h late every day?

Answer

Answer: Simon Collins

Hi

Thanks for your question. The easy answer is that you will probably be fine.

Both the drugs in PrEP stay in your body to allow for a few hours being late with dosing.

It is better to try to take them at the right time.

The after sex doses with on demand dosing only need to be taken 24 hours and 48 hours after the first double dose. Taking an extra dose for a third day will not do any harm though.

If you are still having sex every day though, then continue taking PrEP until 24 and 48 hours after the last time you had sex.

More information on real life examples for on demand dosing.