Question

When are symptoms of PEP failure expected?

4 January 2023. Related: All topics, PEP/PEPSE.

If someone has finished taking PEP, and it has not worked, when do signs start to show up?

Answer

Answer: Josh Peasegood

Hi, how are you doing?

If PEP fails, it will postpone seroconversion and the symptoms associated with it. For this reason symptoms would be expected 1-3 weeks after finishing PEP. Symptoms are not very specific and is commonly caused by other infections e.g., cold and flu. In 1 in 5 people they will not experience any symptoms at all.

Please see this link for more information about PEP:
https://i-base.info/qa/factsheets/pep-faq

Josh.

2 comments

  1. Josh Peasegood •

    Hi Biswajit, no this is not a sign that PEP has failed.

  2. Biswajit •

    I was complete my pep 28days and next days start rash on my body small small red rash on body I think pep not working