Question
Can I take berberine while taking Biktarvy?
6 February 2026. Related: All topics, Drug interactions.
Hi there
Can I take berberine while taking biktarvy. I’m pretty diabetic and wanted to start taking berberine.
Answer
Hi there
Unfortunately I don’t have an easy answer to your question.
This is because I couldn’t find berberine listed on the Liverpool University Drug Interaction website:
hiv-druginteractions.org/checker
A Google search said that berberine is processed by your body using liver enzymes (including CYP 3A4) that is also used by some of the drugs in Biktarvy – notably bictegravir.
Based on this limited information, please DO NOT use berberine until a pharmacist looks at whether this ls likely to be a significant interaction.
I will update this page if I learn more after contacting the Liverpool group.
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