Question
What can I do about darkening of the skin and thinning of the limbs and face?
3 April 2009. Related: All topics, Side effects.
I am on Truvada and nevirapine for HIV, I am also on a preventetive antibiotic Septrin, because my CD4 count is below 200 (i.e 156). I was dignosed with TB but have since finished treatment for TB. My problem is that since I started treatment I developed changes in my body that might be noticed by those who knew me before. Changes include darkening of skin, especially face, thinning of face, arms and legs. Are these changes due to the medication I am taking? If yes, what can be done with the problem? Thank very much and keep on doing the good job you are doing for us.
Answer
Thank you for your question.
Darkening of the skin may be a result of low levels of vitamin D. I have replied to a similar question here. Hope you find the answer useful too.
As for the thinning of the face, legs, etc, this may be a condition called lipodystrophy. There is a very detailed information about it here.
Please note that taking the ARVs is still very important, as your CD4 count is still low. Your doctor may decide to make changes after you talk to him/her. It is important, however, that you do not interrupt or change medicines on your own.
Hello Zay and many thanks for getting in touch.
I am sorry you are dealing with this, but it seems to be very common and reversible.
In the literature I researched it seems to be reversible within months of years after completing the treatment.
In the first instance what you need to know is that it’s best to use sunblock in all areas of your face and body exposed to the sun.
You can also speak to your doctor as the darker skin might also be attributed to some vitamin deficiency, which is easy to correct when identified.
It’s also important to discuss with your doctor as they might have more suggestions about this.
Hi.I have been on TB meds for nine months.I had light skin and after the TB treatment im gone so so dark.Its seven months since im off all meds but very little improvement in my skin.Any suggestions going forward