i-base

P

PrEP

PrEP (Pre-Exposure Prophylaxis) – using HIV drugs before sex (and after) to stop the chance of infection. UK guide to UK – a 24-page i-Base guide covering PrEP in detail. How to use PrEP. Buying PrEP online. Essential monitoring tests. Dosing options including …

PI (protease inhibitor)

PI (protease inhibitor) – a type of HIV drug. HIV protease inhibitors include atazanavir, darunavir, fosamprenavir, indinavir, nelfinavir, lopinavir/r (Kaletra), ritonavir, saquinavir and tipranavir. Drug targets in the virus life cycle Different protease inhibitors have been developed to treat hepatitis C.

postpartum

postpartum refers to the time after a baby is born. Postpartum refers to the mother. See: antepartum and intrapartum.

phenotype test

phenotype test – a type of drug resistance that tests whether a drug is sensitive or resistance to a sample of HIV.

partially active

partially active – the HIV treatment in question will work against this virus but this is reduced compared to wild-type HIV. This is the same as partial resistance, or intermediate resistance etc.

primary mutation

primary mutation – see major mutation.

phenotype

phenotype — relating to how an organism behaves, based on how its genotype relates to the environment. Phenotypic resistance tests look at whether HIV continues to grow in a test tube after increasing concentrations of a drug are added. See …

point of care

point of care – referring to you doctors office (or wherever you access care)

PEP

PEP (Post-Exposure Prophylaxis) – a short course of HIV treatment to HIV to reduce the chance of infection. See prophylaxis and PrEP.

Preclinical testing

preclinical refers to the early development stage for a new drug, before any testing on humans. This includes they laboratory and animal tests. Preclinical studies will not always show what will happen when people use the drugs, but can provide …

Placenta

placenta – the placenta is a temporary organ that develops in pregnancy and joins the mother and foetus. The placenta acts as a filter. It transfers oxygen and nutrients from the mother to the foetus, and takes away carbon dioxide …

pulmonary

pulmonary – relating to the lungs.

publication bias

publication bias – the tendency for published results to be different to other trials. For example, trials that show a positive effect are more likely to be reported and published than trials that find no effect.

protozoa

protozoa – a single-celled animals that are larger and more complex than bacteria.

prophylaxis

prophylaxis – a treatment taken before an illness in order to prevent it occuring. Primary prophylaxis is the terming for taking a preventative treatment before ever having had the illness. Secondary prophylaxis is the term for continuing to take a …

prenatal

prenatal – before birth. The time in which the foetus (developing baby) grows in the uterus.

prematurity (pregnancy)

prematurity (pregnancy) – when a baby is delivered after only 37 weeks or less.

Portacath

Portacath – a small medical device fitted under the skin that allows injected drugs to have a more direct route to where they are needed.

peripheral neuropathy (PN)

peripheral neuropathy (PN) – damage to the nerves in your hands or feet. PN can be caused by HIV or some HIV drugs. Peripheral neuropathy – more infomation.

platelet

platelet – a blood cell that helps with blood clotting.

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