i-base

T

TasP – Treatment as Prevention

TasP (Treatment as Prevention) – a term to emphasise the impact that HIV drugs (ART) has on dramatically reducing the chance of HIV transmission. ART is firstly for the health of the HIV positive person. But having an undetectable viral load …

Tenesmus

A feeling that your bowl not completely empty even though it is empty. A medical definition is “a sensation of incomplete bowel evacuation despite an empty rectum”. The marvels of latin and medicine – words for everything…

TD (or tid)

TD (or tid) – a short hand term for medication dosing that means ‘take three times a day’. See also q8H.

tropism

tropism – the type of coreceptor used by HIV in order to attach to and then infect a cell. If HIV uses the CCR5 coreceptor on the surface of the a CD4 cell it is called R5-tropic. If it uses …

treatment-naive

treatment-naive – someone who has never taken any anti-HIV treatments before. (Note: people who are treatment naive can still be resistant to anti-HIV drugs if they were infected with a drug resistant strain of HIV}.

treatment-experienced

treatment-experienced – someone who has previously used anti-HIV treatments.

TST

TST – abbreviation for testosterone

TST

TST – tuberculosis skin test

Treat as non-pregnant adult

treat as non-pregnant adult – Treat as non-pregnant adult is a very common phrase in HIV and pregnancy. This means that generally your HIV is treated as if you were not pregnant. There are some exceptions, particularly when you do …

Transmission of HIV

transmission of HIV – see HIV transmission

Type-2 diabetes mellitus (T2DM)

type II diabetes mellitus (T2DM) – an illness that usually affect adults (previously called adult-onset diabetes), when glucose levels increase because the body does not produce enough insulin or does not respond well to insulin.

trimester

trimester – a 12 week period of a pregnancy. Different periods during pregnancy are commonly referred to as the first, second and third trimester.

triglycerides

triglycerides (TG) – a kind of lipid (blood fat) that is generated by the liver. Untreated HIV infection reduces triglicerides and treatment increases levels again. Some HIV drugs also increase triglycerides.

toxoplasmosis (toxo)

toxoplasmosis (toxo) – an opportunistic infection caused by a protozoa. The risk to develop toxo increases after CD4 counts fall below 100 cells/mm3. Toxo section of the training manual.

TB (tuberculosis)

TB (tuberculosis) – a bacterial infection that commonly affects the lungs (pulmonary TB) but which can also affect most other organs. TB section of the training manual.

T-cell

T-cell – a type of white blood cell (lymphocyte) that are part of the immune system and that mature in the thymus (T). CD4 cells are also called T-cells.

Tmax

Tmax – the time taken for a drug to reach the highest (maximum) concentration. What happens when you take a drug?

T1/2 (half-life)

T1/2 (half-life) –  the time taken a drug to clear from the highest concentration to half this level. Drugs have different half-lives in different compartments (ie half-life in blood can be different from the half-life inside a cell). It take …

toxicity

toxicity – medical word for side effect, the potential harm a drug can cause.

thrombocytopenia

thrombocytopenia – a low platelet count (platelets help stop bleeding by clotting blood).