Q and A

Question

Why does my CD4 count go up and down?

I’ve been HIV positive for 4 Years. I am not on HIV medicine. My 1st CD4 count was 545, since then it’s been up to 1225 and down to 725. My last CD4 was 1083. And my viral load is 1000. What is the reason my CD4 count goes up and down? What is my life expectancy?

Answer

Everyone’s CD4 count goes up and down. For example CD4 counts are lower when you wake up, and higher later in the day. They are higher just after exercise, and they are affected by diet or having other infections too.

None of these changes mean that your immune system is stronger or weaker. A CD4 count between 500 and 1200 is strong. For someone who is not on treatment, a viral load of 1000 is also very low.

However, here in the UK HIV treatment guidelines recommend starting HIV treatment (ART) at any CD4 count. This is because ART can help to keep your health strong whatever your CD4 count is.

Now in 2016, HIV medicines are safe and effective, so many people on ART now can have a normal life expectancy.

You can find out more about ART and starting treatment here.

Best wishes,

Roy

12 comments

  1. Josh Peasegood

    Hi Tobias, as your viral load remains undetectable it means your treatment is still working. When was your CD4 count last in a healthy range (430-1630)? Have your results been reviewed by a doctor? As HIV is being suppressed by your treatment, it is possible that there is another reason for this drop in CD4 count. Do you also have a CD4 percentage? This is usually a better measure for the healthy of your CD4 count.

  2. Tobias

    Hi,

    I am on medication for my HIV since over 5 years. My recent tests in the last 9 months have all showed a very low CD4 count of around 250 going down to now 214. My viral load remains undetectable. Under 50 copies.
    I am worried because obviously CD4 counts of under 200 generally mean you have AIDS.
    Should I be worried? What actions can I take to get my CD4 up. FYI my CD4 counts have never been amazing. I think my highest was nearly 800.

    Any advice would be greatly appreciated.

    T

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