Q and A


CD4 drop

Hi, I was diagnosed HIV positive July last year and have been on treatment for almost a year (August, 2016 – June, 2017).

My cd4 count has increased from 130 to 230 (after three months, using Norvir+Truvada+Prezista) and to 290 (after 6 months, switched to Triumeq).

But now it drastically falls to 230 (after 9 months) and 198 (after 10 months). Worse still, my skill problem (a lot of acne on my face and neck) seems to rebound. I also feel tired recently. If this decrease persists (30 per month), I will die within half a year. I feel terrified.

Can someone tell me what could be the reason for such decreases. Is there anything I can do to help rebuild my immune system and boost my CD4 count? Is my skin problem really associated to my CD4 count? Any solution for ease the acne?


Thanks for getting in touch.

Firstly, try not to panic, you aren’t going to die.

Other than the issues that you’re having with your CD4, which could be due to several reasons, (Please see here):


What’s your current viral load? And what is your viral load history? If its undetectable, it means that the meds are working. This is even if your CD4 is fluctuating.

With regards to the ache, was this ever a problem before you were positive? Also when you say tiered, have you had any changes in life style?

Information on this website is provided by treatment advocates and offered as a guide only. Decisions about your treatment should always be taken in consultation with your doctor.


  1. Lisa Thorley

    Hi Ashi,

    The only way to boost a CD4 is by taking meds, which you’re doing. And doing very well.

    As the following post explains there isn’t a known link between taking ARVs and acne. Therefore, this is something that you should talk to your doctor about.


    I think its important not to panic. Have your CD4 retested.

  2. Ashi

    Hi Lisa, thanks for your quick reply!! It is very helpful.

    My viral load has been undetectable since last October (after three months treatment). I have never got so many pimples before being positive. I know that my face is a reflection of my body condition. When the cd4 count falls, my pimples get worse… my lifestyle remains the same and I’m even bearing less stress than last a few months. And my docotor told my to lead a same lifestyle as I used to have.

    But as my cd4 decreases to under 200, my body becomes very vulnerable to various deseases. Is there anyway I can boost my cd4?

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