Glossary

revertant mutation – this term is used in two ways.

Firstly when referring to a genetic change that shows the virus is returning from a drug resistant mutation back to a wild-type genotype. This can sometimes take several stages. For example, T215E/D/E and S are revertant mutations that can indicate the drug resistant mutation T215Y is being replaced by wild-type (i.e. T215T).

It can also refer to the fitness of a virus. A revertant mutation can refer to an additional mutation that allows the virus to regain viral fitness (most drug mutations also make the vurs less fit). The second example is called a compensatory mutation as is compensates for the reduced fitness caused by the first mutation.

bradycardia is when the heart beats too slowly.

tachycardia refers to when the heart beats too fast.

See: arrhythmia

lymph node – small bodies in the lymphatic system, particularly at the neck, armpit, and groin, that filter bacteria and foreign particles. During infection, lymph nodes may become swollen with white blood cells (lymphocytes) fighting the infection.

C-section – Caesarean section, procedure to deliver a baby that involves making a cut through the abdominal wall to surgically remove the infant from the uterus.

multi-disciplinary – a team approach to care, involving several different professionals.