Glossary

cirrhosis – severe scarring of the liver (see fibrosis) that makes it difficult for the liver to carry out its functions

viral tropism see tropism.

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.

Hickman line – a fixed central line that is used to deliver IV drugs close to where they are needed in the body.

somnolence – feeling sleepy or drowsy, especially during the day.