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Glossary

Selected words and phrases

fixed dose combination (FDC) – several drugs combined in one tablet at a standard dose.

KS – Kaposi’s sarcoma.

Cancer: lymphoma and sarcoma.

PI (protease inhibitor) – a type of HIV drug.

HIV protease inhibitors include atazanavir, darunavir, fosamprenavir, indinavir, nelfinavir, lopinavir/r (Kaletra), ritonavir, saquinavir and tipranavir.

Drug targets in the virus life cycle

Different protease inhibitors have been developed to treat hepatitis C.

cross-resistance – when resistance to one drug causes resistance to other similar drugs.

This commonly happens for every class or family of HIV drugs: nukes, NNRTIs, PIs, integrase inhibitors and entry inhibitors.

acute infection – early infection (first few months with HIV).