Summary of Product Characteristics (SPCs) – detailed information about a drug provided by the maker that is approved by the European Regulatory Agency (EMEA/CPMP). Also called EPARs.
Glossary
Selected words and phrases
jaundice – a common symptom of hepatitis where increased levels of bilirubin lead to a yellowing of the skin or eyes.
preclinical refers to the early development stage for a new drug, before any testing on humans. This includes they laboratory and animal tests. Preclinical studies will not always show what will happen when people use the drugs, but can provide a guide to serious problems that could occur.
X-ray – an abbreviation for x-radiation. An X-ray lung scan is a common way to look for evidence of TB infection. X-rays can also diagnose bone fractures.
seroconversion – the immune reaction when you develop antibodies to a new infection. HIV seroconversion usually starts a couple of week after infection. Because this is when viral load is very high (often millions of copies/mL), this is when symptoms occur.
About 70% people have HIV seroconversion symptoms. Some people become very ill and need immediate ART, and other have no symptoms.