Glossary

Intermediate level resistance – when a drug still has some impact on HIV, but when this is reduced (compared to wild-type HIV) because there is some drug resistance.

acute infection – early infection (first few months with HIV).

low level resistance – when there is some resistance but it does not have any significant impact on how well a drug works.  The HIV drug is still sensitve and is  considered active.

axis – line on a graph to measure data. Graphs usually have a vertical axis (y-axis) and horizontal axis (x-axis). An axis should show what is being measured and the units of measurement, eg ‘time (in minutes)’.

PI (protease inhibitor) – a type of HIV drug.

HIV protease inhibitors include atazanavir, darunavir, fosamprenavir, indinavir, nelfinavir, lopinavir/r (Kaletra), ritonavir, saquinavir and tipranavir.

Drug targets in the virus life cycle

Different protease inhibitors have been developed to treat hepatitis C.