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Glossary

Selected words and phrases

Cmax – highest concentration of a drug after a dose.

What happens when you take a drug?

cross-over study – where patients in a study ‘roll-over’ to a second related study. For example, this can be after a fixed period in a study (ie after 48 weeks) or after another event (for example, not having a treatment response).

cholesterol – kind of lipid (blood fat).

fusion inhibitor – a type of HIV drug (an entry inhibitor). Fusion inhibitors stops HIV ‘fusing’ to a CD4 cell. T-20 (enfuvirtide, Fuzeon) is only currently licensed fusion inhibitor.

Drug targets in the virus life cycle.

KS – Kaposi’s sarcoma.

Cancer: lymphoma and sarcoma.