Stevens-Johnson Syndrome – a type of severe rash that is luckily rare. This rash has been reported in 0.1–0.3% of people using NNRTIs. It can also occur with other drugs including antibiotics (including cotrimoxazole/Septrin). Any rash on an NNRTI should be shown to your doctor to decide whether treatment needs to be switched or can continue.
Glossary
Selected words and phrases
half-life (T1/2) the time taken a drug to clear from the highest concentration to half this level. Drugs have different half-lives in different compartments (ie half-life in blood can be different from the half-life inside a cell). It take 5 x the half-live for a drug to be considered cleared.
methadone – a man-made opiate that used to treat heroin addiction. See also buprenorphine.
Ctrough – another word for Cmin.
spinal tap – See lumbar puncture.