Glossary

second-line therapy – the combination of used after your first treatment has failed.

secondary mutation – see minor mutation.

fulminant liver disease – sudden, rapid disease progression related to liver failure.

half-life (T1/2) the time taken a drug to clear from the highest concentration to half this level. Drugs have different half-lives in different compartments (ie half-life in blood can be different from the half-life inside a cell). It take 5 x the half-live for a drug to be considered cleared.

What happens when you take a drug?

fibrosis – mild to moderate scarring of the liver (see cirrhosis)