Glossary

HPV (human papillomavirus) – a family of viruses associated with cervical cancer and anal cancer and genital warts.

entry inhibitor (EI) – class of anti-HIV drug.

Drug targets in the virus life cycle.

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.

free radical – a chemical produced after a molecular reaction, often containing oxygen, that has one ‘free’ unpaired electron on its outer surface. This makes it able to react and damage other cells, and perhaps increase progression of cardiovascular disease, cancers and aging. See antioxidant.

Immune reconstitution inflammatory syndrome – see: IRIS