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Glossary

Selected words and phrases

percentage (%) – a number as a proportion of 100.

qualitative (in a study) – where what is being measured either fits one of several categories, or includes descriptive results.

escape mutation – a mutation or change in the genetic structure of HIV that makes it easier to evade the persons immune system (rather than a mutation that stops an HIV drug from working).

blood sugar – glucose in the blood. When carbohydrates are digested they produce glucose, which circulates in the blood and is used by the body as fuel.

elite controller (EC) – if your viral load stays undetectable for more than five years without ART you are an elite controller.

Elite controllers also have a very good CD4 count (always above 500 cells/mm3) that stays at a similar level over many years.

Even with this good immune response, ART is still generally recommended in the long-term.

This is because over decades – some ECs have been undetectable for more than 20 years – there is a concern that low level HIV in different body compartments like the brain, might lead to accumulative serious damage that isn’t easy to detect until it is too late.

This is a real concern, though evidence is limited because of the rarity of ECs.

See: long-term slow progressor (LTSP)/long-term non-progessor (LTNP).