Glossary

drug resistant mutation – a mutation or change that occurs in the HIV genome that reduces a drugs ability to work.

nucleotide – the building blocks of the genetic code (DNA/RNA). Also called a base.

cirrhosis – severe scarring of the liver (see fibrosis) that makes it difficult for the liver to carry out its functions

fixed dose combination (FDC) – several drugs combined in one tablet at a standard dose.

stage (staging) – the stage of hepatitis infection refers to the amount of scaring (fibrosis), from results from a biposy. It is usually measured on the Metavir scale of 0 to 4, where 0 represents no scarring and 4 cirrhosis, or on the Knodell scale of 0 to 6, where 0 is no scarring and 6 cirrhosis. See grading.