Glossary

autoantibody – abnormal antibodies produced against the body’s own tissues.

Ctrough – another word for Cmin.

in-vivo – a study carried out in humans.

Area Under the Curve (AUC) – total exposure to drug over the dosing period.

CD4% – percentage of total lymphocytes (white blood cells) that are CD4 cells.

The CD4% is generally more stable than the CD4 count. For example, if you ever get a CD4 count that is much lower than you expect, first see whether the CD4% has changed too,

If the CD4% is still roughly the same then the low CD4 count is unlikely to show a real change.