Glossary

treat as non-pregnant adult – Treat as non-pregnant adult is a very common phrase in HIV and pregnancy. This means that generally your HIV is treated as if you were not pregnant. There are some exceptions, particularly when you do not need treatment for your own HIV and concerning some of the commonly used HIV drugs.

revertant mutation – this term is used in two ways.

Firstly when referring to a genetic change that shows the virus is returning from a drug resistant mutation back to a wild-type genotype. This can sometimes take several stages. For example, T215E/D/E and S are revertant mutations that can indicate the drug resistant mutation T215Y is being replaced by wild-type (i.e. T215T).

It can also refer to the fitness of a virus. A revertant mutation can refer to an additional mutation that allows the virus to regain viral fitness (most drug mutations also make the vurs less fit). The second example is called a compensatory mutation as is compensates for the reduced fitness caused by the first mutation.

virion – the name for a virus when it is not inside a cell, for example when new viral material leaves a CD4 cell and is floating in blood or plasma

point of care – referring to you doctors office (or wherever you access care)

ascites – an abnormal accumulation of fluid in the abdomen, a sign of serious liver damage in people with hepatitis C.