Glossary

treatment-experienced – someone who has previously used anti-HIV treatments.

EBD (event-based dosing) – a term for taking medicines only at times linked to a relevant event.

EDD is also called “on-demand dosing”.

For example, EBD for PrEP (to prevent HIV transmission) involves taking PrEP before sex and then for several days after sex. EBD for PrEP is only appropriate in some situations and for some people – otherwise daily dosing is recommended.

• Event-based oral dosing (2:1:1 or 2:7)
• Real-life examples for on-demand dosing
• Daily PrEP dosing

Area Under the Curve (AUC) – total exposure to drug over the dosing period.

low level resistance – when there is some resistance but it does not have any significant impact on how well a drug works.  The HIV drug is still sensitve and is  considered active.

neonate – a baby that is 0 to 28 days old.