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Glossary

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hepatic encephalopathy – brain disease that occurs when serious liver damage prevents toxic substances from being flitered out of the blood, and they enter the brain. See encephalopathy.

T1/2 (half-life) –  the time taken a drug to clear from the highest concentration to half this level. Drugs have different half-lives in different compartments (ie half-life in blood can be different from the half-life inside a cell). It take 5 x the half-live for a drug to be considered cleared.

What happens when you take a drug?

STI (sexually transmitted infection) – other STIs include herpes, gonorrhoea and syphilis etc.

Stevens-Johnson Syndrome – a type of severe rash that is luckily rare. This rash has been reported in 0.1–0.3% of people using NNRTIs. It can also occur with other drugs including antibiotics (including cotrimoxazole/Septrin). Any rash on an NNRTI should be shown to your doctor to decide whether treatment needs to be switched or can continue.

central line – tube inserted into a deep vein to deliver medicine (Hickman line or PortaCath).