Glossary

preclinical refers to the early development stage for a new drug, before any testing on humans. This includes they laboratory and animal tests. Preclinical studies will not always show what will happen when people use the drugs, but can provide a guide to serious problems that could occur.

NASBA (nucleic acid sequence based amplification) – a type of viral load test.

virological failure – the term for when viral load levels never reach undetectable, or if they rebound to higher levels after previously being undetectable. See clinical failure.

monotherapy – using only one drug.

malignant – dangerous. A malignant cancer is a dangerous cancer that is growing.