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Glossary

Selected words and phrases

mixed feeding – combination of breastfeeding and bottle feeding.

selective pressure – this is when a factor in the environment causes one type of organism to develop and grow in preference to another. With HIV drug resistance, the presence of a drug exerts selective pressure for resistance to develop. It is based on evolution and the concept of ‘survival of the fittest’ theory developed by Charles Darwin.

major mutation – a drug resistance mutation that have a big impact on whether a drug continues to work. This used to be called a primary mutation.

phenotype test – a type of drug resistance that tests whether a drug is sensitive or resistance to a sample of HIV.

CMV (cytomegalovirus) – a viral infection. CMV retinitis is an HIV-related infection that can cause permanent vision loss in someone with a CD4 count that is below 50 cells/mm3.

More information on CMV.