Glossary

open label – this means that a patient in a trial knows which treatment they are taking.

uneven distribution – a term in statistics where most results fall to the left (positive skewness) or right (negative skewness) of the middle of the range.

genotype test – a test that looks at how the genetic structure of a sample of HIV and whether the virus has changed with drug resistant mutations.

high level resistance – when an HIV drug no longer works against the virus.

SVR (sustained virological response) – having a negative HCV viral load test 6 months after stopping HCV treatment. The response, 6 months after treatment is stopped, determines whether treatment has been effective in terms of clearing HCV. SVR is the most important result from an HCV treatment trial. See ETR.