Glossary

minor mutation – a drug resistance mutation that have a big impact on whether a drug continues to work. This used to be called a secondary mutation.

blip – small, occasional increase in viral load.

cirrhosis – severe scarring of the liver (see fibrosis) that makes it difficult for the liver to carry out its functions

high level resistance – when an HIV drug no longer works against the virus.

treatment-naive – someone who has never taken any anti-HIV treatments before. (Note: people who are treatment naive can still be resistant to anti-HIV drugs if they were infected with a drug resistant strain of HIV}.