Pulmonary hypertension refers to high blood pressure in the arteries taking blood from the heart to the lungs.
People living with HIV-are more likely to develop pulmonary hypertension than HIV-negative people.
Glossary
Selected words and phrases
KS – Kaposi’s sarcoma.
Food and Drug Administration (FDA) – the US FDA is the government organisation that is responsible for approving and regulating human and animal medicines in the US. It is also responsible for the safety of other products including foods, cosmetics and tobacco.
See: www.fda.gov
On-demand dosing – a term for taking medicines only at times linked to a relevant event.
On-demand dosing for PrEP is also called “event-based dosing” (EBD).
For example, on-demand dosing for PrEP (to prevent HIV transmission) involves taking PrEP before sex and then for several days after sex.
For many years, on-demand dosing referred to 2:1:1 dosing. This was an option for cisgender gay and bisexual men using PrEP. This involves starting with a double dose (two pills), taken 24 to 2 hours before sex, and then single daily doses for the two days after sex.
In 2025, UK (BASHH) and European (EACS) PrEP guidelines included 2:7 on-demand dosing for cis and trans women and other transgender and non-binary people.
ribavirin – drug used to boost the efficacy of pegylated interferon to treat hepatitis C. Given as twice-daily capsules.