NRTI – Nucleoside Reverse Transcriptase Inhibitor, a type of HIV drug – also called ‘nuke’ or ‘nucleoside analogue’.
3TC (lamivudine). abacavir, AZT, FTC (emtricitabine), d4T (stavudine), ddI (didanosine) all belong to this class.
Tenofovir DF and tenofovir alafenamide (TAF) are a nucleotide analogues which is similar enough to be counted as part of this class.
Drug targets in the virus life cycle.
bacteria – single-cell micro-organisms without a nucleus.
compensatory mutation – this refer to an additional mutation, usually in the context of the fitness of a virus. For example, the mutations that stop a drug form working often stop the virus from reproducing as well. Additional mutations that return the virus to it’s former fitness are called compensatory mutations. They compensate for the reduced viral fitness. See revertant mutation.
fibrotest – a test which uses results from blood tests to predict liver damage and which may become an alternative option to liver biopsy in some patients.
adherence – taking your medicine at the right time each day and in the right way.