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Glossary

Selected words and phrases

null hypothesis – in a study this sometimes just refers to the hypothesis, but more specifically it refers the idea that any difference between 2 study groups has only occurred by chance.

prematurity (pregnancy) – when a baby is delivered after only 37 weeks or less.

triglycerides (TG) – a kind of lipid (blood fat) that is generated by the liver. Untreated HIV infection reduces triglicerides and treatment increases levels again. Some HIV drugs also increase triglycerides.

encephalitis – inflammation of the brain.

tropism – the type of coreceptor used by HIV in order to attach to and then infect a cell. If HIV uses the CCR5 coreceptor on the surface of the a CD4 cell it is called R5-tropic. If it uses the CXCR4 co receptor it is called R4-tropic). Early HIV infection is usually R5-tropic but over time, especially in late disease (if CD4 counts drop to less than 50 cells/mm3) the virus shifts to being X4-tropic.  Mixed tropic refers to a having some viruses that use R5 and some that use X4.