Glossary

Area Under the Curve (AUC) – total exposure to drug over the dosing period.

combination therapy – using three or more drugs together to treat HIV. It is also called triple therapy, cART (combination antiretroviral therapy)  or HAART (highly active antiretroviral therapy).

cryptococcus (crypto) – a fungal infection. Can cause meningitis.

partially active – the HIV treatment in question will work against this virus but this is reduced compared to wild-type HIV. This is the same as partial resistance, or intermediate resistance etc.

matched – in clinical trials matched refers to each group having similar age, gender, ethnicity, HIV duration, health etc in a study.