Glossary

fold-change – a term relating to drug resistance after a phenotype resistance test.

4-fold resistance (also called a 4-fold loss in sensitivity) means you need to use four times the dose to get the same reduction in viral load.

prematurity (pregnancy) – when a baby is delivered after only 37 weeks or less.

fibrosis – mild to moderate scarring of the liver (see cirrhosis)

PT (prothrombin time; pro-time) – PT testing measures the amount of time it takes for blood to clot. When the liver is damaged, its ability to make clotting factors is impaired. If this time increases – referred to as a prolonged PT interval – it shows that the liver is not working so well.

virion – the name for a virus when it is not inside a cell, for example when new viral material leaves a CD4 cell and is floating in blood or plasma