Glossary

CART – combination anti-retroviral therapy.

clinical cut-off (CCO) – a test result that is associated with an impact on clinical care. With resistance tests a lower CCO is the level below which a drug is still sensitive or active. This is often set at a 20% loss of activity (compared to wild-type HIV). An upper CCO is the level above which the drug is not considered active (ie resistant). This is often set at an 80% loss of activity (compared to wild-type HIV).

IQR (inter-quartile range) – when using (median) average, the IQR gives an indication of the spread or range of results. Each quartile (1st, 2nd, 3rd and 4th) represents 25% of the results. The IQR represents the middle 50% of the results. See also range.

coinfection – having more than one infection, eg HIV and TB, or HIV and hepatitis C.

adefovir – anti-viral drug used to treat hepatitis B.