cross-resistance – when resistance to one drug causes resistance to other similar drugs.
This commonly happens for every class or family of HIV drugs: nukes, NNRTIs, PIs, integrase inhibitors and entry inhibitors.
Glossary
Selected words and phrases
CCR5 inhibitor – type of HIV drug (an entry inhibitor) that blocks HIV from getting into a CD4 cell. CCR5 is a co-receptor on the surface of a CD4 cell that HIV uses to attach itself to the cell. CCR5 inhibitors block that process. Maraviroc is currently the only approved CCR5 inhibitor.
publication bias – the tendency for published results to be different to other trials. For example, trials that show a positive effect are more likely to be reported and published than trials that find no effect.
sarcoma – medical term for cancer that affects bone, cartilage, fat, muscle, blood vessels, skin or other connective tissue.
ChemSex is a common term used by gay men for drug use that includes at least one of these three recreational drugs: meth, meph and G.
- Methamphetamine (crystal/crystal meth/Tina/meth).
- Mephedrone (meph/drone).
- GHB/GBL* (G, Gina).