Glossary

ARV – a drug that works against a retrovirus, eg treatment for HIV. See: antiretroviral.

duration of ruptured membranes – time between when the mother’s waters break and the actual delivery.

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.

fusion inhibitor – a type of HIV drug (an entry inhibitor). Fusion inhibitors stops HIV ‘fusing’ to a CD4 cell. T-20 (enfuvirtide, Fuzeon) is only currently licensed fusion inhibitor.

Drug targets in the virus life cycle.

mL (millilitre) – a measure of a volume of liquid. 1000 millititres = 1 litre.