Glossary

TD (or tid) – a short hand term for medication dosing that means ‘take three times a day’.

See also q8H.

baseline – baseline refers to the start of any period being studied. For someone who is HIV positive, their baseline CD4 and viral load counts are the first tests they ever had taken. For someone entering a study, the baseline results refer to their test results at the start of the study. Baseline results for following resistance refers to the results of the first resistance test.

virus – an infectious organism that can only reproduce inside the cell of another plant or animal.

ARV – a drug that works against a retrovirus, eg treatment for HIV. See: antiretroviral.

clinical cut-off (CCO) – a test result that is associated with an impact on clinical care. With resistance tests a lower CCO is the level below which a drug is still sensitive or active. This is often set at a 20% loss of activity (compared to wild-type HIV). An upper CCO is the level above which the drug is not considered active (ie resistant). This is often set at an 80% loss of activity (compared to wild-type HIV).