Glossary

intent-to-treat analysis (ITT) and on-treatment analysis (OT) – two important ways that trial results are analysed. ITT includes all patients who entered the study and is more rigorous. OT only calculates the response rates for people still on the randomised treatment.

PT (prothrombin time; pro-time) – PT testing measures the amount of time it takes for blood to clot. When the liver is damaged, its ability to make clotting factors is impaired. If this time increases – referred to as a prolonged PT interval – it shows that the liver is not working so well.

nuke – a common term for NRTI

mortality – medical word for death or dying.

Peripheral arterial disease refers to a narrowing or hardening (atherosclerosis) in the arteries in the arms or legs.

See: atherosclerosis