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Glossary

Selected words and phrases

resistance – when the genetic structure of an organism (virus, bacteria, fungi etc) changes in a way that stops a drug from working. See mutation.

Changing treatment and drug resistance.

INI (integrase inhibitor) – type of HIV drug.

Drug targets in the virus life cycle.

asymptomatic – showing no signs of illness.

fungus (fungi) – parasitic organisms that include moulds, mildews, mushrooms and yeast.

DAA (direct acting antiviral) – new hepatitis C drugs that work directly against the hepatitis C virus (HCV).

The following links are to UK prescribing information for DAA combinations plus ribavirin.

Elbasvir/grazoprevir
https://bnf.nice.org.uk/drugs/elbasvir-with-grazoprevir/

Sofosbuvir/ledipasvir
https://bnf.nice.org.uk/drugs/ledipasvir-with-sofosbuvir/

Glecaprevir/pibrentasvir
https://bnf.nice.org.uk/drugs/glecaprevir-with-pibrentasvir/

Sofosbuvir/velpatasvir 
https://bnf.nice.org.uk/drugs/sofosbuvir-with-velpatasvir/

Sofosbuvir/velpatasvir/voxilaprevir
https://bnf.nice.org.uk/drugs/sofosbuvir-with-velpatasvir-and-voxilaprevir/

Ribavirin (RBV)
https://bnf.nice.org.uk/drugs/ribavirin/

Additional information is available from the MHRA website.
https://products.mhra.gov.uk/