fold-change – a term relating to drug resistance after a phenotype resistance test.
4-fold resistance (also called a 4-fold loss in sensitivity) means you need to use four times the dose to get the same reduction in viral load.
Glossary
Selected words and phrases
Atherosclerosis refers to a narrowing or hardening of large and medium sized arteries.
The narrowing is caused by a build-up of plaque, and usually takes many years.
As the walls of the artery thicken, the heart has to work harder to pump the same amount of blood through a narrower gap.
malaria – a parasite infection of red blood cells.
immune system – the system that your body uses to fight infections.
CCR5 inhibitor – type of HIV drug (an entry inhibitor) that blocks HIV from getting into a CD4 cell. CCR5 is a co-receptor on the surface of a CD4 cell that HIV uses to attach itself to the cell. CCR5 inhibitors block that process. Maraviroc is currently the only approved CCR5 inhibitor.