HIV and hepatitis coinfection

Update on chronic hepatitis C in HIV/HCV-coinfected patients: viral interactions and therapy

This 5,000 word report provides a nice review of key topics in HCV/HIV co-infection. It is written by Norbert Brau, treating physician at Bronx VA Hospital, NYC. Here is the list of topics covered.

  1. Significance of HCV in the HIV-infected population
  2. Prevalence of HIV/HCV-coinfection
  3. Interactions between HIV and HCV infection:
    • Influence of HIV infection on the course of chronic hepatitis
    • Influence of HCV infection on the course of HIV disease
  4. Treatment of chronic HCV in HIV/HCV-coinfected patients
  5. Lactic acidosis
  6. Special considerations in HCV therapy for HIV-infected persons
  7. Which HIV/HCV-coinfected patients should be treated for chronic hepatitis C and how?
  8. Management of HIV/HCV-coinfected patients with end-stage liver disease:
    • Treatment for decompensated liver disease
    • Liver transplantation
  9. Future research questions

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