December 2003

Contents

Editorial

• Volume 4 Number 10 December 2003

Conference reports

• 9th European AIDS Conference (EACS), 25-29 October 2003, Warsaw

• Lower doses of d4T produce similar efficacy and reduced side effects

• Switching from efavirenz to nevirapine to avoid CNS side effects

• Interruption of treatment is safe for those who started too early

• T20 is cost effective for UK purchasers

• Intrauterine exposure to efavirenz

• African patients and adherence in the UK

• Five-year results of Kaletra-based therapy in treatment-naïve HIV patients

• IL-2 effectively increases CD4 count in people with low CD4 nadir

• Hepatitis coinfection: incidence in Europe and response to transplant

• Rituximab plus CDE for HIV-related Non-Hodgkins Lymphoma (NHL)

Antiretrovirals

• FTC (emtricitabine, Emtriva) approved in Europe

• EMEA recommend approval for atazanavir for treatment experienced patients

• Fosamprenavir (Lexiva) approved in US

• US paediatric, adult and maternal-child guidelines updated

Treatment access

• Access to treatment – some progress…

• WHO approves combination pills

• South African Competition Commission finds GSK and BI responsible for ‘excessive pricing’ and ‘abuse of market position’

• Access to HIV treatment in Eastern Europe

Paediatric care

• Dramatic decline in mortality, disease progression and hospital admissions in children with HIV infection in the UK and Ireland

• New tool for assessing risks of disease progression and death based on age, CD4 percentage and viral load in HIV-infected children

Side effects

• Increased risk of myocardial infarction associated with duration of protease inhibitor treatment

Weight, diabetes, metabolic complications

• Polylactic acid (New-gill) repairs facial wasting and improves quality of life

Hepatitis coinfection

• UK guidelines for treating coinfection with HIV and hepatitis B or C published online

• Kidney and liver transplantation in HIV-infected patients: case presentations and review

• London epidemic of sexually transmitted hepatitis C

Vaccines and microbicides

• VaxGen AIDSVAX vaccine fails in Thailand

On the web

• Conferences

• Online medical lectures

• Newsletters and reports

• HIV and hepatitis coinfection

• Other news

PDFs

• Volume 4 Number 10 December 2003/January 2004 PDF