US Guidelines on prevention and treatment of opportunistic infections updated (2009)

The following US guidelines have been updated and are available online:

Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents: Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America.

Unfortunately, unlike the main US treatment guidelines, this updated document does not highlight in the text the changes from earlier documents.

However, the introduction states that major changes include:

  • Greater emphasis on the importance of antiretroviral therapy for the prevention and treatment of OIs, especially those OIs for which no specific therapy exists;
  • Information regarding the diagnosis and management of immune reconstitution inflammatory syndromes;
  • Information regarding the use of interferon-gamma release assays for the diagnosis of latent TB infection;
  • Updated information on drug interactions that affect the use of rifamycin drugs for prevention and treatment of TB;
  • The addition of a section on hepatitis B virus infection; and
  • The addition of malaria to the list of OIs that might be acquired during international travel.

Links to other websites are current at date of posting but not maintained.