US Guidelines on prevention and treatment of opportunistic infections updated (2009)
The following US guidelines have been updated and are available online:
Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents: Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. http://www.hivatis.org
Unfortunately, unlike the main US treatment guidelines, this updated document does not highlight in the text the changes from earlier documents.
However, the introduction states that major changes include:
- Greater emphasis on the importance of antiretroviral therapy for the prevention and treatment of OIs, especially those OIs for which no specific therapy exists;
- Information regarding the diagnosis and management of immune reconstitution inflammatory syndromes;
- Information regarding the use of interferon-gamma release assays for the diagnosis of latent TB infection;
- Updated information on drug interactions that affect the use of rifamycin drugs for prevention and treatment of TB;
- The addition of a section on hepatitis B virus infection; and
- The addition of malaria to the list of OIs that might be acquired during international travel.