Case study of COVID-19 in HIV positive person with history of HCV

Simon Collins, HIV i-Base

With so few reports of outcomes of COVID-19 in HIV positive people yet available, case reports are important, in this case in someone with a history of HCV.

This was a 38-year-old Chinese gay man diagnosed with COVID-19 on 25 January who had travelled to Wuhan several weeks earlier. He had been diagnosed with HIV in 2016 with a CD4 count of 84 cells/mm3 and HCV coinfection.

The case included persistently negative SARS-CoV-2 RNA on specimen samplings but positive for plasma anti-SARS-CoV-2 antibody although these were delayed.

Ref: Zhao J et al. Early virus clearance and delayed antibody response in a case of COVID-19 with a history of co-infection with HIV-1 and HCV. Clinical Infectious Diseases, ciaa408, DOI: 10.1093/cid/ciaa408. (09 April 2020).

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