Debate over development of pathogenic strains of CoV-2
In the last couple of weeks different research groups have presented various analyses on whether or not CoV-2 mutated into a more pathogenic and easier to transmit form.
Related articles are included below.
Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2.
Korber B al. bioRxiv. doi: 10.1101/2020.04.29.069054
This 33-page report raises concerns that the virus has mutated into a more severe from. Although from established researchers (with a history of HIV-related research), it is a bioRxiv preprint that has not been peer reviewed.
SARS-CoV-2 viral spike G614 mutation exhibits higher case fatality rate
Manuel Becerra-Flores and Timothy Cardozo, Int J Clin Pract. 2020 May 6. doi: 10.1111/ijcp.13525.
This study from NYU supports the more pathogenic mutation from Korber et al.
The problem with stories about dangerous coronavirus mutations.
Yong E. The Atlantic.
A new report that is critical of the findings.
Details discussed in Twitter thread
Trevor Bedford (from Fred Hutchinson/https://nextstrain.org/).
Some coronaviruses can reinfect the same person quickly: will that happen with SARS-CoV-2?
Mark Mascolini report for NATAP.org
Study finds nearly everyone who recovers from COVID-19 makes coronavirus antibodies.
Francis Collins, NIH Directors Blog.
Antibody responses to SARS-CoV-2 in patients with COVID-19.
Long QX et al. Nat Med. (29 April 2020).