Reviews on immunology of COVID-19

Simon Collins, HIV i-Base

The following two reviews are useful overviews on current approaches to understanding immunology of COVID-19.

Immunology of COVID-19: current state of the science. Immunity (2020).
Vabret N et al. j.immuni.2020.05.002. DOI: 10.1016/j.immuni.2020.05.002

This review summarise the current state of knowledge of innate and adaptive immune responses from SARS-CoV-2 and the immunological pathways that are likely to contribute to disease severity and death.

It also discusses the rationale and clinical outcome of current approaches to treatment and is sufficiently updated to include all recent remdesivir studies. It also reviews some of the prospective clinical trials to prevent or treat SARS-CoV-2 infection.

The many faces of the anti-COVID immune response.
Vardhana SA et al. JEM, 216(6) (30 April 2020).

A review of active vs innate immune activation and COVID-19, that also cautions about this being an IL-6-mediated cytokine release syndrome.

Links to other websites are current at date of posting but not maintained.