HTB homepage • Conference reports • Articles by subject • Subscribe December 2001 Contents Conference reports 3rd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Athens, 23-26 October 2001 Insulin resistance Thyroid function abnormalities Lipodystrophy and metabolic changes in children Bone studies at lipodystrophy workshop Antiretrovirals Delaying antiretroviral therapy may be considered for many patients Correlation between reduction in plasma HIV1 RNA concentration 1 week after start of antiretroviral treatment and longerterm efficacy One week on, one week off experimental regimen might reduce the cost and toxicities of HIV therapy Enteric coated didanosine significantly reduces nausea, bloating, GI upset Secondary mutations in HIV-1 protease predict treatment failure in naive patients Antiretroviral regimen complexity, self-reported adherence, and HIV patients’ understanding of their regimens: survey of women in the HERS study Study indicates NNRTI mutations have little effect upon HIV-1 replicative capacity Treatment access Survey reveals pregnant Zambians support universal nevirapine treatment Paediatric care Syncytium inducing viral phenotype halves thymic T cell production in children Children with advanced disease who take HAART experience immune reconstitution PK and drug interactions Garlic can impede HIV medication Caution needed with nelfinavir and some lipid-lowering drugs Guidelines New US guidelines for the prevention of opportunistic infections in people infected with HIV Side effects Elevated blood pressure in subjects with lipodystrophy Fat distribution is strongly tied to metabolic disturbances in HIV lipodystrophy Eating more often can reduce cholesterol levels Coinfections and complications Incidence and prognosis of AIDS-related lymphoma have improved since the advent of HAART TB coinfection Coinfection does not appear to augment TB infectivity Basic science and immunology Detailed picture emerges of how HIV travels into and out of cells High levels of HIV replication shut down anti-HIV immune responses Natural killer cell activity varies with viral burden in HIV-1 infection Other news MDMA: acute effects of ecstasy on T-cell numbers and function TRAIL ligand induces apoptosis of cells infected with HIV in-vitro DHEA replacement therapy improves quality of life Medicinal plant ‘fights’ AIDS On the web Review: treatment of chronic hepatitis PDFs Volume 2 Number 10 December 2001 PDF HTB homepage • Conference reports • Articles by subject • Subscribe
