April 2006

Contents

Editorial

• Volume 7 Number 4 April 2006

Treatment alerts

• Important renal safety information regarding the use of tenofovir and Truvada

Conference reports

• Further reports from 13th Conference on Retroviruses and Opportunistic Infections (CROI), 5-8 February 2006, Denver

• Pharmacokinetics of antiretrovirals in pregnancy: tenofovir, nelfinavir, lopinavir/r

• Risk of central nervous system birth defects associated with ART exposure during pregnancy

• No increase in adverse pregnancy outcomes in Thai women receiving nevirapine-containing HAART

• ARV treatment following singe dose nevirapine exposure

• Association of HIV replication capacity with mother to child transmission

• Association between HIV subtype and detection of K103N

• Pharmacology and drug interaction studies in adults: summary table from CROI, ICAAC and EACS conferences

• Other new antiretrovirals at Denver: the future seems bright

• Origins of HIV traced to chimpanzees in Cameroon

• HSV-2 suppression reduces HIV and HSV shedding

Pipeline report

• HIV/HCV coinfection: re-treating hepatitis C in people coinfected with HIV

Treatment strategies

• Treatment interuption arm in DART trial is stopped early

Treatment access

• Treatment access new from Aidspan

• China puts 23 HIV/AIDS patients under house arrest

PK and drug interactions

• Nelfinavir reduces pravastatin AUC by 46% in HIV negative volunteers

Guidelines

• NICE publishes TB guidelines in UK

TB coinfection

• WHO launches new stop TB strategy

Other news

• Community responses to mainstream US magazine supporting HIV denialists

On the web

• Online analysis of recent PK news

• 12th Annual BHIVA Conference abstracts

• Full text journal publications online

PDFs

• Volume 7 Number 4 April 2006 PDF