PK Workshop 11th 2010

11th International Workshop on Clinical Pharmacology of HIV Therapy, 7-9 April, 2010, Sorrento, Italy

Atazanavir absorption maximised with food

Methadone levels reduced moderately by rilpivirine

Maraviroc 150mg once-daily achieves target concentrations with atazanavir/ritonavir

Raltegravir and unboosted atazanavir

Raltegravir dose adjustment not required for patients on dialysis

Raltegravir and darunavir pharmacokinetics in liver disease

Tenofovir may require closer renal monitoring in older patients

Effect of age on atazanavir, darunavir, raltegravir and etravirine

Proposed approach to measuring TDM for raltegravir

Increased bilirubin levels when atazanavir is dosed twice-daily