Question

PrEP and antibiotics are very safe and effective if taken together.

There are no drug interactions and both meds will continue to work really well.

This link to a guide about PrEP  has a lot more info:
https://i-base.info/guides/prep

12 comments

1. Prety • 3 December 2025

   Do Metronidazole interact with prep. Can i take it while on prep

2. Pretty • 3 December 2025

   Can i take Metronidazole antibiotic interact with prep. Im on prep was prescribed metronidazole

3. Simon Collins • 1 September 2025

   Hi Jesus, there are no drug interactions between thse meds.

4. Jesus • 1 September 2025

   If I am taking Amoxicillin while I am on prep. My levels of prep in my body reminds safe to protect me?

5. Josh Peasegood • 10 June 2024

   Hi Natasha, yes you can take PrEP and azithromycin. There is no interaction between these two drugs.

6. Natasha • 10 June 2024

   Can I take azithromycin with prep

7. Josh Peasegood • 24 February 2024

   Hi Tanim, yes you can take these medications together.

8. Tanim • 24 February 2024

   Hi can I take FLUCLOIXACILLIN with PrEP

9. Lisa Thorley • 14 January 2021

   Hi Kyle,

   This should be OK. However, before you take any other medication it’s important to know if there could be an interaction. The following site will help: https://www.hiv-druginteractions.org/checker

10. Kyle • 14 January 2021

    Can I take antibiotics while on hiv treatment if I got infected with STD