Question

Should I extend 2:1:1 PrEP if I was late with some doses?

1 February 2022. Related: Adherence, All topics, PrEP.

Currently I tam aking PrEP on demand 2-1-1, somehow I misread the info. I thought the second dose is 24 hours after sex where actually is 24 hours after first dose. I took the second dose late by 9 hours from the actual schedule. My question is, should I worry about the late schedule on the second dose by 9 hours? Is this affected the efficiency? If yes, what should I do? I took Truvada for the PrEP on demand. Thank you!

I chew the tablet because I really can’t take tablets, is this a problem also?

Thank you so much!

Answer

Answer: Josh Peasegood

Hi, how are you doing?

While being late for your dosing is not ideal, you would still have some protection. If you have continued with the schedule you won’t need to do anything else.

PrEP dosing also allows for some flexibility. This includes continuing for additional doses on day 5 and 6 is you want to do this. This just means using daily dosing for a few days.

This is a link to a guide about on-demand dosing.

Chewing a tablet is fine. What’s important is that you ingest it. If you are unable to swallow the tablet before chewing, that is not a problem and is safe to do so.

Josh.