Question
Do PrEP and omeprazole interact?
2 February 2022. Related: All topics, Drug interactions, PrEP.
I have been on daily PrEP since the original trials but have now been put on Omeprazole to combat stomach acid. Is there anything I should know about interaction between the two?
Answer
Hi, how are you doing?
Are you using Truvada for PrEP? If you are there is no interaction between PrEP and omeprazole. You are safe to take them both.
Josh.
Hello Gus and thank you for getting in touch.
The simple answer is that both are right.
Tegoprazan interacts with some ARVs, just not the ones used for PrEP (tenofovir and emtricitabine).
If, however, you need to take PEP please be aware to inform the pharmacist as there might be interactions with this new combination.
Hi guys, what about Tegoprazan? It’s like omeprazole but newer, also for ulcer treatment. Does it interact with Tenofovir 245 mg / Emtricitabina 200 mg PrEP? I’ve read in the Tegoprazan pamphlete that it should not be taken with HIV treatment but I asked the PrEP doctor and he said it was ok. I’m confused, does anybody know an answear for this?
Hi Richard, what time are you taking these meds?
Ulcer treatment will change the acid level in the stomach which can reduce how effective PEP is if taken at the same time.
To prevent this interaction it is recommended to take them at opposite ends of the day e.g., PEP in the morning and ulcer treatment at night. This will prevent any risk of interaction.
As a minimum ulcer treatment should be taken no sooner than 6 hours before or 2 hours after PEP.
hi, i’am on ulcer treatment is ok to take Omeprazole, neurobion and gastica while on pep
Hi Charles, yes you can take these medications together. There is no interaction between any of them.
Hi can I take truvada, raltegravir (pep) and omeprazole?
Hi Paul, this will depend on which meds are in the PEP. The last two drugs are nibiotics nd re fine. The first drug though is an antacid which cn interact with protease inhibitors. Please ask our doctor or pharmcist to check.
Can h pylori drugs (lansoprazole, amoxicillin and clarithromycin) be taken together with PEP?
Hi Shelia, there are no interactions between Ranega and Omeprazole. It is safe to take these drugs together.
M taking Renaga (ARVS) it’s safe to take omaprazole?