Question
How do I reverse the body changing side effects from ART?
23 June 2022. Related: Access to treatment, All topics, Side effects.
When I started my ART, I got disfigured. I.e My legs became thin, the tummy bulges and the face grows bigger abnormally. The skin also darkens in a funny way. Nails have lost their white colour.
Based on this, some people can easily know that you are on ART. What can I do to reverse these side effects.
Answer
Hi, how are you?
What ART are you on/were on? Older HIV medication like d4T and AZT are known for causing the side effects you have mentioned. If you have not already, switching to newer HIV medication combinations will be the best way to prevent any further changes.
Unfortunately reversing these side effects can be slow. It may also not be possible to fully reverse them but there are a number of options.
Building muscle in sites of lost fat can help to replace how the body looks. This can be difficult and take time but can be of benefit. As for the face, have you considered ‘fillers’? There is a specialised treatment called NewFill which has been designed for people that lost weight in their face due to older HIV drugs.
An earlier Q&A discusses this in detailĀ here.
Josh.

Hello Phumzile and thanks for getting in touch.
Please see my responses here: https://i-base.info/qa/20028
Nutrition options to improve my weight on my bums and legs l am very thin and visible veins on my legs
Hello Phumzile and thanks for getting in touch.
I am sorry to hear you don’t feel comfortable with your body.
Here you can read somme more information on Lipoatrophy (fat loss):
https://i-base.info/guides/side/fat-loss-lipoatrophy
You could benefit from exercise and healthy dieting while rebuilding your muscles.
Please see below a few more information:
https://i-base.info/guides/side/diet-a-balanced-diet-and-your-health
https://i-base.info/guides/side/exercise-and-staying-active
In some countries a combination of treatments are employed to deal with that issue, including injectable face fillers.
Please discuss available treatments with your doctor and clinic
I need to refill my face and legs changed by the first regement of ARV
Hi Lebogang, if you are in the UK then please ask your doctor for a referral to the Chelsea anfd Westminster Hospital in London. Ther is likely to be a waiting list but it is available. I am sorry I dont have info about access in other countries. If New-fill is for HIV-related weight loss it should only be given by someone who has been trained for HIV. It is very different to when used to cosmetically treat wrinkles.
Where can I get newfill to reduce the loss of weight in my face due to older HIV drugs and also in my legs as my daughter always ask me why my legs looks so thin and I was not born like that