Q and A


I have started PEP and want to know if I will be okay?

I had sex with a transexual man. I was on top and without me realizing the condom had ruptured, I washed myself and went home. But I did not feel comfortable. So I sent a text asking the man I had just had sex with if he was HIV positive, to which he answered, yes. I freaked out and went inmediately to the internet and did some research. I read about PEP, so the next morning I went to the clinic and I was placed on – Truvada 200 mg, Norvir 100 mg and Reyataz 300 mg. This was 36 hours after the incident.

I have had no side effects. But for the last two days, I have felt as if I have some fever. I tested my temperature and it is within the normal parameters of 98.2 and 98.7. Please tell me do I have a shot to be well? The person I had sex with told me that his viral count is below 40. Please help.


Thank you for your question.

I am sorry to know that you are distressed. What is important is that you have taken the right steps to giving yourself a chance of remaining  uninfected. PEP is effective the earlier that you take it and should be taken within 72 hours of being exposed to HIV. You started PEP within that time frame.

Additionally, as the person who you had sex with is on treatment with an undetectable viral load, then your chances of an HIV infection are much more reduced than if that person was not on treatment.

If you take the PEP as prescribed this will reduce the small chance that you were exposed to HIV.

Symptoms do not occur this soon after an exposure.

Good luck.


  1. Josh Peasegood

    Hi David, for information about transmission please see here: https://i-base.info/qa/factsheets/hiv-transmission-and-testing

  2. David

    Can someone get HIV from someone who as it without eny cut

  3. Josh Peasegood

    Hi Steve, as the sex worker has said she is HIV negative there is no reason to doubt this. Trisbuss is effective as PEP. STDs can increase the risk of HIV transmission but it does not make the risk ‘insanely high’. Please see here for more information: https://i-base.info/qa/factsheets/hiv-transmission-and-testing

  4. Steve

    Hi there!

    Unfortunately I had a night of sex with a sex worker without protection which was due to a lot of alcohol..

    The sex worker claims she isn’t HIV positive however this only concerns me more that she may be in the acute stage.

    After roughly 40 hours I started taking pep and was prescribed Tribuss in South Africa. I have now finished the 28 day course and I’m insanely worried about having an HIV test..

    I definitely picked up chlamydia and potentially syphilis and am taking Doxycycline for 14 days to address both of these…

    I read a lot online that Tribuss is ineffective as PEP and the chances of catching HIV with other STD’s is insanely high.

    Can you please confirm the effectiveness of Tribuss as pep and the chances of me testing positive in the upcoming test..

  5. Simon Collins

    Hi John


    Please see this factsheet on PEP that answers your Qs:

  6. John

    Hi I’m John,

    I had unprotected sex with a lady who I found out post encounter that is HIV positive and is yet initiate treatment. I was only able to access PEP around 33hrs after exposure and started right away. On day 26 now and side effects of tiredness and fatigue are gone. What are my prospects of success as I have sticked to prescribed treatment all times and never missed doses?

  7. Simon Collins

    Hi Claire,

    Please see this factsheet on PEP that answers your Qs:

    The condom means you are not at risk so in the UK you wouldnt have been prescribed PEP.

    You started in time for this to still work though, so please don’t worry.


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