Question
Is it ok if I take my meds 15 or 30 mins late?
10 October 2016. Related: Adherence, All topics.
Do you have to take your arvs at exactly the same time each day? Will for example 30 mins (or even an hour) each way have any impact whatsoever on the suppression of the virus or cause resistance? I am worried as even though I take them every day some days it is 15 or 30 mins later or earlier than the previous day.
Answer
Thank you for your question.
It is sometimes difficult to take your meds at the exact same time everyday.
Even when starting, there is a window of about an hour either side of your target time when it is still fine to take them.
For example, if you want to take your meds every night at 10 pm, then any time between 9pm and 11pm will be fine.
Everyone has a few times when we forget our meds though.
The less this happens the better. But if it does happen once in a while then there is nothing to worry about. If you forget in the future, take them as soon as you remember. However, if this is already close to the next dose DO NOT take a double dose.
Once you get an undetectable viral load, especially if it has been undetectable for several years, you have more flexibility. This partly depends on which drugs you are using.
Some once daily drugs (including tenofovir DF, emtricitabine and efavirinz) have long half-lives. This means drug levels stay in your body for long enough to cover being several hours late or even missing a dose completely.
Several studies are looking at whether reduced dosing might be safe – for example by only taking ART for four days a week. We need bigger studies before we know if this is safe though.
Note: this question was updated in October 2016 from and original answer in April 2011.
I was two minutes late from taking my ARVs can that affect my viral load? I take tenofovir lamivudine efavirinz
Hi Sipho,
What medication is it that you’ve been given to take? If part of your combination is efavirenz, the way that you’re feeling is common. Its your bodies way of getting used to the medication. These side effects should go within a few weeks of starting medication. If they don’t you’ll need to see your doctor. There’s more info here about starting medication: http://i-base.info/guides/starting
Good Afternoon .I tested Positive and My Cd4 count Was Less than A 100 before i took My meds .. The week Passed took My meds well And Ive discoverd That I Experience All these Side Effects At the same time Worse is that i still go to work and I stress alot … i lack Sleep Aswel Pls Help
Hi Kram,
As long as its not on a regular basis, this will be fine.
Hi, may i ask if its ok to take arv 5 hours late? My Arv is Lamivudine/tenofovir DF efavirenz.. Thanks for the answer
Hi Dudu,
Its not ideal to miss 2 days of meds. However, you should be fine. Are you now back on your medication?
I’ve been missing my hiv pills for 2 days can that thing affect me
Hi ntombizodwa,
As long as your viral load is undetectable there won’t be any risk. Please see here: http://i-base.info/u-equals-u/ Do you know what your viral load is?
If im using ARVs and my partner is HIV negative will he also get infected if the condom burst ?
Hi Alex,
It’s good that your meds are working and you’re undetectable.
Your meds should be fine. Maybe you should always just take them at 8 or 9 am and 8 or 9 pm. You can allow yourself a window around your time slot. I could be about an hour earlier or later.