Question

New medications…

17 April 2006. Related: All topics, Changing treatment, Resistance.

New medications – what are the new medications that will be available in the UK and the US?

Answer

Answer: Simon Collins

There are five new drugs or formulations that have either been approved recently or are close to being approved, or are available in expanded access programmes.

1. Tipranavir was the most recent drug to be approved in Europe (in October 2005). Tipranavir is a protease inhibitor, which works against HIV that is resistant to current protease inhibitors. It needs to be used with a small boosting dose of ritonavir, like most other protease inhibitors. and used in a combination with other drugs that are active.
2. Darunavir (also called TMC-114) is likely to be approved later this year, but is available now on expanded access. Darunavir is a protease inhibitor that also works against HIV that is resistant to othe PIs.
3. Kaletra is going to be replaced by a new formulation that requires fewer pills, and which doesn