Question
I have a question about side effects and just started treatment?
19 May 2013. Related: All topics, Side effects.
I just started Odimune last night, when I wake up during night I was feeling dizzely and my vagina outside lips burning. vagina lips are still burning, I only have this problem just have after taking Odimune.
Answer
We get lots of questions similar to this.
In general, if you have any symptoms this is something to talk to your doctor about.
i-Base can provide information but we can’t diagnose symptoms.
Although some symptoms can be side effects, sometimes they are related to other things.
Odimune includes an ARV called efavirenz, and this can make you more anxious and worried. This link has more information on efavirenz:
https://i-base.info/guides/side/cns-side-effects
No ARVs have side effects that include vagina pain so this sounds like something to ask your doctor about.
Links to other common side effects questions are here:
https://i-base.info/guides/side

hello Ceee and thanks for getting in touch.
PrEP should not cause such a sensation.
PrEP is a single tablet combining the two medication (active substance) Tenfovir Disoproxil and Emtricitabine, regardless of the brand name used.
However, I feel there might be two possible scenarios:
Either you have a reaction to somme of the excipients (other substances incorporated in the tablet form with the main active substance) in which case it would make a difference which brand you use.
If that’s what’s happening, I would recommend using the brand you had no reaction to.
The other possibility is that your burning sensation is caused by another infection, possibly sexually transmitted.
I would urge you to have a full sexual health screen to exclude this possibility.
I used PREP (hetemcit) before but stopped because of the burning in my vagina and bum. This year I tried to take prep again (Emtricitabine and Tenofovir) the burning came back I could not take it, it just to much to handle, I stopped again…Tenemine prep did not cause the burning thou but the other 2 I mentioned above is just not good, please help and try to fix this problem.
Hi Jose, thanks, without more dietails it is difficult to comment on the pain. You might just be very sensitive to one or both of these drugs. What sis the doctor who prescribed these meds say?
This is not a common response though. Millions of people take these meds every day without these problems.
In the UK you can report side effects yourself using the Yellow Card Scheme.
https://yellowcard.mhra.gov.uk
I have the same symptom. I am a male, I started prep with tenofovir/emtricitabine (Movitrem in my country) about 3 monrhs ago, I presented with a burning pain in perianal, perineal AND glans after a few hours of taking the first pill.
The second day the pain became horrible so I had to stop the medicación, resolving the pain 24 hours after i stopped prep. Yesterday I decided re-try the medication in order to reduce my risk of hiv, However again, this burning pain apppear.
It Is obviously associated with tenofovir and/or emtricitabine. Somebody should report it
Hello Carol and thanks for getting in touch.
No, you shouldn’t feel this way and you should have a doctor take a look.
This can be related to some infection that happened to start at the same time as PrEP.
It needs to be assessed and treated accordingly
I hope you will feel better soon
Hi I took prep this morning for the first time , and 1hour later I have a burning virgina and now it moved outside on the sides of my privates and bums , I cannot stand the pain anymore, I used prep named Hetemcit, please help , is it normal