Question

I have a question about side effects and just started treatment?

I just started Odimune last night, when I wake up during night I was feeling dizzely and my vagina outside lips burning. vagina lips are still burning, I only have this problem just have after taking Odimune.

Answer

We get lots of questions similar to this.

In general, if you have any symptoms this is something to talk to your doctor about.

i-Base can provide information but we can’t diagnose symptoms.

Although some symptoms can be side effects, sometimes they are related to other things.

Odimune includes an ARV called efavirenz, and this can make you more anxious and worried. This link has more information on efavirenz:

https://i-base.info/guides/side/cns-side-effects

No ARVs have side effects that include vagina pain so this sounds like something to ask your doctor about.

Links to other common side effects questions are here:

https://i-base.info/guides/side

38 comments

  1. Simon Collins

    Hi Gee, all the info we have on PEP is here:
    https://i-base.info/qa/factsheets/pep-faq

  2. Gee

    I also started prep 17 November at 21:00 about 23:30 when I was about to sleep I felt a very sharp burning down there,It lasted whole day I couldn’t even sit or stand still for it was burning as if I rubbed chillies down there,Couldn’t even sleeep.I did not take the pill the next day and the burning came down it literally stopped.

  3. Christina Antoniadi

    Hello Thuli and thank you for getting in touch.

    I am not sure if you are referring to vaginal symptoms or some other side effects.

    In general it is good to inform your doctor about any side effects.

    In i-base we are not doctors and cannot diagnose symptoms.

    What we hear often however is that some times other infections such as vaginal thrush or other STIs might cause these symptoms.

    It is best to visit a sexual health clinic as they can give you creams and treatment for any infection that might be present.

    You can read more here about side effects:
    https://i-base.info/guides/side/what-are-side-effects

  4. Thuli

    I’m also experiencing the same thing

  5. Christina Antoniadi

    Hello Sonia and thank you for the question.

    I am very sorry you are having such a bad experience.

    In general, if you have any symptoms this is something to talk to your doctor about.

    i-Base can provide information but we can’t diagnose symptoms.

    Although some symptoms can be side effects, sometimes they are related to other things.

    What medication are you using for PrEP?
    This reaction is not documented for generic Truvada PrEP to the best of my knowledge.

    It might be that some other infection is also present (thrush for example can cause extreme discomfort).

    I would suggest to speak with a doctor or pharmacist as they can give you some topical cream to relieve the symptoms.

    Links to other common side effects questions are here:

    http://i-base.info/guides/side

  6. Sonia

    I started prep lastnight 14 September, I took my first pill past seven and woke up around 1 with my vagina and anus burning. I haven’t slept at all. I am now soaking in the bathtub. Please help: how do I make this go way?

  7. Christina Antoniadi

    Hello Tee and thank you for the comment.

    I am very sorry you have had this dismissive experience from the healthcare system.

    Are you able to tell me what medication you are referring to?

    ARVs are generally well tolerated and I am not aware of any reports of symptoms like the ones you are mentioning.

    ARVs keep you healthy and provide a good quality of life.

    The names of the medication you take will help me understand better what might be the problem

    If you prefer to continue the conversation in private please e-mail me here: questions@i-base.org.uk

  8. Tee

    I took my first pill last night around 10:00 pm and woke up around 1:00 am with itchy, burning, sore vagina and anus. There’s definitely a link and I do not understand how long we will be gaslighted till they establish what and how to treat or prevent this. I’m stopping with immediate effect. How long will this last ladies? I can’t take it anymore

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