Q and A

Question

Can dolutegravir add to anxiety?

My doctor recently switched me from dolutegravir to raltegravir, which I take along side Descovy (FTC/TAF). The doc says dolutegravir can add to anxiety and isn’t as good for my central nervous system.

Have you heard of this effect from dolutegravir?

I am a white men aged 53. I’ve been positive for 6 years in January and I was luckily diagnosed at seroconversion.

Answer

Hi there

Thanks for your question and for including these details.

Your doctor is giving you good information.

Although most people find dolutegravir very easy to take, about 5% of people (1 in 20) find it changes their mood. This can include anxiety.

Raltegravir is not linked to this side effect.

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