Question
Late with the after sex on-demand PrEP dose.
5 March 2022. Related: Adherence, All topics, PrEP.
Hello for all. I started 2-1-1 prep, took 2 pills 3 hours before sex. Then I took second pill after 24 hours after sex, not 24 hours after the first 2 pills – I have delayed the second pill by 3 hours. I’m still continuing taking PrEP every day because I have sex but I am just worrying is it ok to delay the second dose by 3 hours? Thank you for reply.
Answer
Hi, how are you doing?
Being 3 hours late on the second dose is not likely to cause a problem. The initial double dose will have increased the drug levels within your body more than a single dose anyway. These drugs tend to remain at the required drug level within the body for more than 24 hours.
While it is best to take the medication as routinely as you can, being late by 3 hours is unlikely to cause you any problem. As you have now continued with daily dosing, PrEP will have remained at effective level within your body.
There is no reason to be concerned after this event,
Josh.
Hi John, on-demand dosing starts with a double dose. The double dose causes a higher level of PrEP in your body than normal.
Though you had forgotten to take PrEP Thursday, you did remember within 12 hours. Due to the double dose initially and the timing of the last dose you are still protected. You are not required to take PEP.
Hi
I forgot 1 pill of prep on demand after sex. Should I be concerned?
Tue 11pm had 2 pills
Wed 8pm had anal sex
Wed 1030pm had 1 pill
Thurs I forgot to eat 1 pill
Fri 8am realized quickly ate 2 pills.
Hi Pete, as you have taken 2 doses of PrEP after sex at a similar time you started your double dose you have taken on-demand PrEP correctly.
You do not need to take any further PrEP pills. You are protected.
Hi
Can I ask a question
I took 2 pills on a Saturday night and had anal sex on Sunday ( I’m active ) I took another prep when I got home at 7 pm and another on Monday but forgot to take a 3rd pill on Tuesday. In summary
Sat. 2 pills
Sunday had sex
Sun 1 pill
Mon 1 pill.
Am I at risk. I’ve only just remembered and it’s now Thursday ( I’ve panicked and just taken two pills)