Medscape article including: Is there a pipeline? and AIDS articles in full

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Recent research in HIV infection: Part 2

AIDS Read 12(12) 2002

Brian Boyle

Discussion of the prevention, diagnosis, and treatment of important coinfections, including herpes simplex virus (HSV), hepatitis B virus (HBV), and hepatitis C virus (HCV).

Less expensive HIV test

AIDS Read 12(12) 2002

Researchers at the Johns Hopkins Bloomberg School of Public Health and the University of Zurich have developed a less expensive test for monitoring the progression of HIV infection during the early stages of disease.

Is there a pipeline? Infections in Medicine

Jeffrey P. Nadler, MD

Several experienced HIV specialists have lamented the dearth of new treatments in the pipeline. I’ve heard this from patients too. The exception is the buzz around T-20 (enfuvirtide). I want to briefly excerpt some information gleaned from many sources at the recent Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), the Infectious Diseases Society of America annual meeting, and the Barcelona AIDS conference to try to dispel the apparent pessimism. Of course, this is far from a comprehensive survey.


Increased risk of lipoatrophy under Stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.
Full text from AIDS:

Multiple measures of HIV burden in blood and tissue are correlated with each other but not with clinical parameters in aviremic subjects
This study looked for levels of residual HIV DNA and RNA in blood and gut reservoirs in aviremic patients, assessed correlations among compartmental measurements of HIV burden, and evaluated association with clinical parameters.
Full text from AIDS:

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