ABC of AIDS – HIV infection and AIDS in the developing world

As in industrialised countries, the spectrum of clinical manifestations associated with HIV infection is wideranging, as the CD4 count falls, from an asymptomatic state, through symptomatic disease, to fatal illness characterised by opportunistic infections, malignancies, neurological disease, and wasting.

Initial acquisition of HIV infection (“acute HIV infection” or “seroconversion illness”) may be complicated by a syndrome resembling infectious mononucleosis, or a wide range of other manifestations, as described in chapter 4. However, since this syndrome is not specific, it is rarely recognised, even when clinically apparent.

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