New ritonavir interactions

15 June 2005. Related: Antiretrovirals.

The ritonavir (Norvir) and Kaletra (lopinavir/ritonavir) package inserts (product labeling) were recently updated to include information regarding interactions with fluticasone (a synthetic corticosteroid, the active component of Flonase nasal Spray) and trazodone (Desyrel, a non-tricyclic antidepressant).

In addition, alfuzosin (an alpha-blocker used to increase the flow of urine in people with benign prostatic hypertrophy (BPH)) was added to the Contraindications section of the ritonavir package insert.

Source: FDA listserve, March 2005