June 2005

Contents

Editorial

• Volume 6 Number 6 June 2005

Conference reports

• 11th BHIVA and BASSH joint annual conference, 22-25 April 2005, Dublin

• Long-awaited UK pregnancy guidelines now updated; pregnancy studies in Dublin

• Underdosing of ARVs in children: results from CHIPS cohort

• Sexual transmission and response to treatment in acute HCV infection in HIV-positive gay men coinfected with HIV

• Levels of efavirenz 10-fold above minimum target level despite coadministration with rifampicin

• Schistosomiasis after immune reconstitution: symptoms appear as HAART side effects

• 6th International Workshop on Clinical Pharmacology of HIV Therapy, 28-30 April 2005, Quebec, Canada

• Effect of age/menopause on lopinavir and efavirenz concentrations in women

• Effect of age on lopinavir concentrations

• Gender and pharmacokinetics of saquinavir

• Dosing nevirapine in children

• Intracellular NRTI-triphosphate levels in children are similar to adults

• Efavirenz and rifampicin: lower body weight associated with higher concentrations

• Summary of drug-drug interaction studies

• Responses to atazanavir, Kaletra and side effects

Antiretrovirals

• 500mg saquinavir (Invirase) approved in Europe

• Roche to withdraw saquinavir soft gel caps (Fortovase)

• FDA approve lopinavir/r once daily for treatment naive patients

• Safety data for tenofovir updated

• FDA approve entecavir for HBV

• Efavirenz warning in pregnancy strengthened

• New ritonavir interactions

• FDA advisory committee recommends approval for tipranavir – material from hearing online

• Application for meltrex formulation of Kaletra submitted to the FDA

Treatment access

• MSF criticises Brazilian government for failing to break antiretroviral patents

• Russian activists imprisoned for asking for treatment – letters of support requested

Guidelines

• US adult treatment guidelines updated (2005)

On the web

• TAC electronic newsletter

• Articles from AIDS Treatment News

• AIDS Vaccine Advocacy Coalition (AVAC) publishes new AIDS Vaccine Handbook

• WHO lists reliable web sites on vaccines

PDFs

• Volume 6 Number 6 June 2005 PDF