HTB homepage • Conference reports • Articles by subject • Subscribe February 2003 Contents Editorial Volume 4 Number 1 January/February 2003 Conference reports 6th International Congress on Drug Therapy in HIV Infection, 17-21 November 2002, Glasgow, UK Combination of three generic drugs in one pill meets bioequivalence criteria when compared with the branded drugs: Triomune vs d4T/3TC/NVP An overview of the conference Pharmacokinetic evaluation of tenofovir and enteric-coated ddI The advantages of fosamprenavir; comparing saquinavir/r to lopinavir/r; reducing viral load to <3 copies; AZT-d4T cross resistance; and rising HCV rates Promising data regarding DermaVir for therapeutic vaccine Enfuvirtide (T-20): predicting success and modelling survival benefits Virologic failure among treatment-naive patients taking tenofovir DF or stavudine in combination with lamivudine and efavirenz Comparison of the efficacy and safety of tenofovir vs. d4T when used in combination with 3TC and efavirenz in ARV-naive patients Safety profile of tenofovir in treatment-experienced patients Antiretrovirals Roche and Trimeris able to make enough enfuvirtide (T-20) for only 12,000 people this year, 32,000 next year, citing difficulties in the manufacturing process Vertex Pharmaceuticals announces submission of NDA/MAA filings in US and Europe for amprenavir pro-drug (GW433908) BMS submits new drug application for investigational protease inhibitior atazanavir Europe and America approve once-a-day stavudine (d4T, Zerit) Tenofovir as HIV prevention: study to reduce HIV transmission in sexually active adults Boehringer chooses dose for phase III studies of tipranavir/ritonavir PI combination Treatment access Lancet special report examines direction new WHO director general should take on several HIV/AIDS-related issues Weight, diabetes, metabolic complications Adipose tissue alterations develop early in antiretroviral therapy Basic science and immunology Breadth of memory CTL response against HIV associated with immune control Dendritic-cell vaccine elicits strong anti-SIV response in monkeys HIV infection causes fibrosis in lymphatic tissue, diminishing CD4+ pool Chronic immune activation: a lethal factor in HIV infection? Other news Website run by a nun in a caravan is nominated for awards Infection by closely related HIV strains possible On the web Report from the 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV The science of side effects (or, who’s afraid of 3T3-F44A2 cells?) Medscape conference coverage, based on selected sessions at the 6th International Congress on Drug Therapy in HIV Infection 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV T-20: a model for novel anti-HIV drugs in development Recent research in HIV infection: Part 1 Medscape coverage: HIV/AIDS-related research at the 40th Annual Meeting of the Infectious Diseases Society of America HIV-associated sensory neuropathies New HIV Insite Knowledge Base chapters Protease inhibitor double boosting Historical essays from Science Treatment of primary HIV infection Lipodystrophy: lack of agreement on definition and etiology presents a challenge to research and therapy Navigating resistance pathways PDFs Volume 4 Number 1 January/February 2003 PDF HTB homepage • Conference reports • Articles by subject • Subscribe