HTB homepage • Conference reports • Articles by subject • Subscribe June 2006 Contents Editorial Volume 7 Number 6 June 2006 Conference reports 7th International Workshop on Clinical Pharmacology of HIV Therapy, 20-22 April 2006, Lisbon Efavirenz levels above recommended upper target in 20% of African patients in Senegal Lower dose of AZT provides adequate exposure in patients with low body weight Pharmacokinetics for generic fixed dose combinations for children are comparable to the branded products Caution against dividing adult FDCs (Triomune) for young children University of Liverpool audit of paediatric TDM Age-dependent pharmacokinetics of 3TC in children Use of small sample drug level monitoring for paediatric PI concentrations Intracellular and plasma measurements of AZT and 3TC and their metabolites in neonates Effect of pregnancy on PK of protease inhibitors Using enzyme inducers to reduce the half-life of nevirapine Relationship between nevirapine concentrations and virological failure in a clinical setting Summary of drug interaction studies Effects of ketoconazole and rifampin on TMC278 Brecanavir interaction study with ritonavir and atazanavir Fixed-dose formulation of efavirenz/tenofovir/FTC bioequivalent to separate dosing Saquinavir/r (1000/100mg) levels reduced when taken fasted and should be taken with food Lack of food effect with Meltrex formulation of lopinavir/r Food interaction reduces ddI intracellular absorption and supports requirement to take fasted Conflicting results on how T-20 affects tipranavir Treatment strategies Autologous stem cells transplant (ASCT) in HIV-positive individuals with a relapsed non-Hodgkins lymphoma (NHL) or Hodgkins disease (HD) Treatment access ITPC publish updated report on access to treatment Protesters evicted from UN headquarters, New York Community opposition filed against tenofovir patent application in India Guidelines US adult treatment guidelines updated (May 2006) Draft BHIVA immunisation guidelines online (2006) TB coinfection HIV linked to lower rifampin and ethambutol AUCs in TB cohort Drug resistance Web resources for HIV-1 genotypic-resistance test interpretation Other news LGV in the UK: almost 350 cases reported and still predominantly affecting HIV-positive gay men On the web Conference abstracts and reports HIV InSite: new chapters PLoS Medicine articles New HIV vaccine website PDFs Volume 7 Number 6 June 2006 PDF HTB homepage • Conference reports • Articles by subject • Subscribe
