HTB homepage • Conference reports • Articles by subject • Subscribe April 2007 Contents Editorial Volume 8 Number 3/4 March/April 2007 Conference reports 14th Conference on Retroviruses and Opportunistic Infections, 25-28 February 2007, Los Angeles Raltegravir (MK-0518) phase 3 trials show successful viral suppression in multi-drug resistant patients Maraviroc phase 2b/3 results in treatment experienced CCR5-tropic patients Phase 2 study of GileadÂ’s integrase inhibitor elvitegravir (GS-9137) Phase 2b study comparing rilpivirine (TMC-278) to efavirenz in treatment-naive patients: 48-week results PK results from heat-stable formulation of ritonavir Use of low-dose rapamycin, a CCR5 suppressant, to increase potency of T-20 in vitro Growth hormone release factor (TH9507) reduces central fat adiposity Further insight into risk and management of cardiovascular disease (CVD) from D:A:D cohort: no additional benefit of metabolic syndrome diagnosis; new HIV-specific CVD risk equations; increasing uptake of lipid lowering drugs but low smoking cessation Pregnancy outcomes in the DART trial 12 month response to HAART in women following exposure to prevention of mother to child transmission regimens Unexpectedly high rate of K65R mutation in patients failing first-line d4T-containing regimens in Thailand Sexual transmission of HCV in Brighton reported in HIV positive and HIV negative MSM Hepatitis B drug entecavir reported to have anti-HIV viral activity in three patients High 6-month rate of PML survival with aggressive use of 5-drug T-20-based ARV regimen Increased anal HPV levels in HV-positive smokers Clade-B HIV-1 infection in Haiti predates global subtype-B virus Drug interactions and pharmacokinetic studies: CROI 2007 Antiretrovirals Darunavir (TMC-114) approved in Europe No significant interaction reported between etravirine (TMC125) and raltegravir (MK-0518) Future of second-generation fusion inhibitors less certain as Trimeris and Roche separate Treatment access Abbott situation worsens in Thailand Guidelines BHIVA launch standards for HIV clinical care (2007) On the web Use of scientific evidence in criminal prosecutions for HIV transmission Articles from AIDS and Medscape Articles from New England Journal of Medicine PDFs Volume 8 Number 3/4 March/April 2007 PDF HTB homepage • Conference reports • Articles by subject • Subscribe