Q and A

Question

How to I manage meds with shift work?

Hi. I started meds (ARVs) not long ago. I take it every night at 20:00.

The problem is that I’m working as a security officer in South Africa. I work 3 days, 3 nights and I go off 3 days. My problem is time balancing since the meds are making me feel dizzy.

Last night was my first night at work since I started meds. So I forgot to take meds with me to work, remembered that I was suppose to take it at 20:00, then I discovered that I forgot it. I knocked off duty in the morning and went home. I made sure that before I sleep as I’m coming from night shift I take my meds at 08:00.

Did I do a right thing, if not what should I do?

Answer

Hi

Thanks for your question which affects a lot of people.

Although you didn’t say the name of your meds, the side effects and timing make this sound like efavirenz.

One of the most widely use single-pill combinations is based on efavirenz, usually with tenofovir DF and emtricitabine in the same pill. The first brand name was called Atripla but there are lots of generic versions.

In the UK, someone working with frequent shift changed would use a different HIV combination. So one thing is to please speak to your doctor to see if there is a choice. Explain how difficult this is to work shifts and say you need a different medicine.

Depending on where your clinic is in South Africa, this might be easy or difficult. Even if it is difficult now (ie to change to a protease inhibitor), in the near future, a combination that is based on a drug called dolutegravir will be easier to use. This is because this will be a similar price to efavirenz and health systems will make this easier to get.

In practice, you did the right thing in taking your meds once you got home,

If your viral load is undetectable now, then you can have a little flexibility with your dose. This is because all three meds stay in your body for longer than 24 hours.

For now, until you can see your doctor, change your dosing to always taking your meds before you sleep. When you alternate shifts, it will be okay to take the meds either earlier or later than 24 hours since the previous dose.

Because of side effects, it will probably be better to extend the time between the new shift dose rather than bringing it forward earlier. This will be much better than trying to work when you are getting side effects form taking an evening dose when working a night shift.

Better if you could change to an easier combination though.

32 comments

  1. Roy Trevelion

    Hi Chandan,

    Please see this Q&A on when will there be a cure for HIV. Scientists are still working hard on this.

    Are you taking HIV meds? Please let us know what meds you’re on and your results for CD4 count and viral load.

  2. Chandan

    Van HIV CURE SOON IN NEAR FUTURE??? I DONT WANT TO DIE EARLY WITH HIV OR AIDS.WILL YOU PLEASE TELL ME CAN ANY PERMENANT AND EFFECTIVE TREATMENT AVAILABLE IN FUTURE.

  3. Lisa Thorley

    Hi Chandan,

    If it’s possible you should be taking an ARV combination that doesn’t contain efavirenz. This is because it’s the efavirenz that require that this medication is taken before going to bed. Are you able to talk to your doctor about the possibility of changing?

    If changing isn’t an option, then you may need to see what it’s like take your meds when you won’t be going to bed. You may not have any side effects.

  4. Chandan

    TENOFOVIR+EFAFIRENZ+LAMIVUDINE SINGLE PILL I TAKE AFTERNOON AT 12 30 PM THEN I GO TO SLEEP,BUT AFTER 1 WEEK I PERFORMED EVENING SHIFT AND 1 WEEK DAY SHIFT…I M VERY COUNSIOUS ABOUT DRUGS.

  5. Lisa Thorley

    Hi Mrinal,

    What medication are you taking? What time of day do you usually take it?

  6. Mrinal

    I started my ART Medicine on 22 may 2019,i am also doing shifting duty can I will able to perform my duty after taking medicine.

  7. Lisa Thorley

    Hi No name,

    What ARVs are you taking?

  8. no name

    I’m hiv positive, but i didn’t start to take my meds . Problem I’m working only night shifts. What time should I take my meds

  9. Roy Trevelion

    Hi Leboh,
    You can see on this question above that a side effect of Atroiza can be feeling dizzy. If you are on night shift it can make work difficult. Can you speak to your doctor about changing your meds so that you don’t feel dizzy at work? A CD4 count of 9 is low. Is it still the same? This can mean that you are likely at risk of infections. You can also talk to the doctor to ask if there are more meds you can take to guard against these infections.

  10. Leboh

    My 1st day to night shift ever sinsce i stated med on 28 march 2018 and im feeling deezy. Is there any thing can happen to me. My med is antroiza if m not mistaken my question is this is there anything can happen to me or having sife effect bcs my cd4 count was too low is 9

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