Question
Are Aluvia and Dumiva the same medications?
27 August 2021. Related: All topics, Starting treatment.
Hi there.
Are Aluvia and Dumiva the same medications?
Answer
Thanks for letting us answer your question online – now posted here:
Aluvia and Dumiva are two different medicines that are often used together to make a complete treatment for HIV.
Aluvia contains lopinavir and ritonavir. In some countries it is called Kaletra.
https://i-base.info/guides/3547
Dumiva contains abacavir and lamivudine. The original versions were called Kivexa or Epzicom.
https://i-base.info/guides/3513
Different drug companies make the same medicines. The different brand names can make it confusing, but these medicines are all just as good. Looking for the active ingredient is the best way to know if your meds have changed.
This link lists some of the most widely used brands in different countries.
Generic HIV drugs
https://i-base.info/guides/12423
Hello Dudu and thanks for getting in touch.
The really good news are that the TLD is working very well for your patient.
There are many reasons for an elevated creatinine.
You need to investigate if your patient:
– is taking any other co-current medication such as herbal and gym supplements, especially creatine and protein supplements – these can interfere with the creatinine readings (repeat the tests after the patient has not taken supplements for 2 weeks)
– if they have been unwell and have taken any NSAIDS before their blood test (and repeat accordingly)
You also should be looking at urine protein/creatinine ratio and albumin/creatinine ratio to establish whether there is kidney damage.
Dolutegravir increases the serum creatinine, however this has no detrimental effect to the kidneys
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.16009
You might need to adjust the dose of metformin or include another anti-diabetic agent as there is an interaction with metformin and dolutegravir.
https://www.hiv-druginteractions.org/checker
How is the creatinine clearance and e-GFR of the patient?
I got patient on TLD with CD4 of 44, rival load 39, creatinine 166 who is also on metformin 1000mg.The creatinine is still elevated. What is the cause of elevated creatinine?
Hello ND and thanks for the question.
Aluvia and Rilovia are the same medication (Lopinavir/ritonavir), but come with different names
I can’t see in the common side effects insomnia but it would be good to discuss with your doctor if this is what you are experiencing.
Sometimes they are able to provide other options for ARVs that might be better tolerated.
See here for more information: https://i-base.info/qa/17548
Hi, im on arv treatment, i take Aluvia and Dumiva, but recently they gave me Rilovia, and i can’t sleep at night at all, i stay awake the whole night, but with Aluvia I’m experiencing this, is it normal?
Hi Sizeka, Rilovia is also the same as Aluvia. They both contain the same medication.
Thank you for the answer because i got the Rilovia instead of aluvia
Hi Zamaswazi, Aluvia and Rilovia are the same medication. They both include lopinovir and ritonavir. They have different names because they are made by different manufacturers. This does not change how the work. The difference is how they look and their name. This will not effect your treatment.
Hi how are you my name is Zamaswazi i have problem I’m taking Aluvia pills then this month they send me Rilovia pills I don’t take them i dont know if it a mistake or it a same thing as Aluvia pills
Hi Nobengazi, Aluvia is lopinavir and ritonavir. Aluvia is the generic name of this combination. Because they are the same there should be no reason for these side effects she is experiencing. How long has she been taking Aluvia for? and does she take any other HIV medication? Has your sister spoken to a doctor about these symptoms?
C M Sega is my sister since October after receiving Lopinavi/Ritonav 200/50mg
At night she react as if she got hot flushes and ichy. Can you assist in this regard but before when Using Aluvia she was fine.