Q and A

Question

Does Atroiza have interactions with TB meds?

I am taking atroiza the fixed dose ARV combination in South Africa so I want to know if it does not have any drug interaction with TB medication?

Answer

Hello,

Atroiza is a once daily combination pill which contains three drugs -efavirenz, emtricibatine and tenofovir. This combination is made by several drug companies and is also called Tribuss, Trustiva, Odimune.  These are all generic versions of Atripla.

This combination can have an interaction with some TB medications that may require a dose adjustment. If Atroiza is co-administered with rifampicin to patients weighing 50 kg or more, an additional 200 mg/day (800 mg total) of efavirenz may be considered. It is important to discuss this with your doctor or pharmacist as this will vary across individuals.

117 comments

  1. sonto

    Hi there when I was taking odimune I used to be sleepy after 1 hour or so but now im on atroiza and I don’t feel any side effect, does atroiza work as a odimune?

  2. sharon

    Hi I’m 21weeks pregnant and have recently found out that I am hiv+,I was given atroiza I jus wana know when and how it should be taken is it 2hours before or after meals?

  3. Rebecca McDowall

    Hi Lucia,
    It is common to feel nauseous when you first start treatment. Your doctor should be able to provide you with anti-nausea medicines to stop this and stop you vomiting. It’s important to discuss this with the clinic and ask for treatment to help with this.

  4. lucia

    Doctor, it is my first time taking atrozia. Is it OK for me to vomit that much, is this 1 of side effect?

  5. Rebecca McDowall

    Hi Nomusa,
    Atroiza is a generic version of Atripla. This means that it is the same treatment but it is made by a different company. It may look or taste different but it will work in the same way and you shouldn’t experience any new side effects. If you do notice any new side effects tell your doctor about these.

  6. nomusa

    I have been using atripla from 2011 December is it wise to change to Atroiza and what are the side effects

  7. Simon Collins

    Hi Christa

    Atroiza includes the same active drugs as Atripla. Atripla is widely used in the UK as an HIV combination treatment.

    Many countries use generic versions like Atroiza.

    See this link from more information.
    http://i-base.info/guides/1561

  8. christa

    I m not quite clear of what Atroiza is for. I know its a drug but what exacly. For HIV /AIDS or. TB.

  9. Rebecca McDowall

    Hi Deekay,
    This isn’t a known side effect of Atroiza so it’s important that you talk to the doctor about this to investigate what the cause might be.

  10. deekay

    Can atrioza cause water retention in legs and feet.

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