Q and A

Question

Does Atroiza have interactions with TB meds?

I am taking atroiza the fixed dose ARV combination in South Africa so I want to know if it does not have any drug interaction with TB medication?

Answer

Hello,

Atroiza is a once daily combination pill which contains three drugs -efavirenz, emtricibatine and tenofovir. This combination is made by several drug companies and is also called Tribuss, Trustiva, Odimune.  These are all generic versions of Atripla.

This combination can have an interaction with some TB medications that may require a dose adjustment. If Atroiza is co-administered with rifampicin to patients weighing 50 kg or more, an additional 200 mg/day (800 mg total) of efavirenz may be considered. It is important to discuss this with your doctor or pharmacist as this will vary across individuals.

117 comments

  1. Bubu

    Hello

    I’d like to know about the side effects of Atroiza?

  2. Robin Jakob

    Hi,

    Tribuss and Atroiza are both generic versions (copies) of a tablet called Atripla. They all contain the same three drugs and work in the same way. They have different names because they are made by the same company.

    You can find more information here:
    http://i-base.info/guides/1561

  3. Mvelwenhle

    Hi guys. If im taking Atroiza is it ok to also take Tribuss?

  4. Robin Jakob

    Hi,
    Yes you should take one Atroiza pill everyday. It is also important to take it as close to the same time as possible. THis is called adherence. It will help your meds work effectively.

    You can find more information here:
    http://i-base.info/guides/starting/adherence

  5. Prudence

    It is my first time using Atroiza. Must i take 1 pill everyday?

  6. Robin Jakob

    Hi,

    It does not matter if you take your pill at 20:00 or 21:00 as long as you take it as close to the same time as possible, and every day. This is called adherence. Being adherent will mean that your meds work effectively.

    You can find more information here:
    http://i-base.info/guides/starting/adherence

  7. Prudence

    Hello. I’m 35 i’ve just started using Atroiza, i want ask if i can take the pill at 20:00 or 21:00?

  8. Robin Jakob

    Hi,

    Tribuss and Atroiza are generic versions (copies) of the same pill. They contain the same medications. They have different names because they are made by different companies.

    Because they are the same pill you can take them. It is important that neither you or your friend miss treatment too often. This can lead to resistance. This would mean that your medication does not work as well.

    You can find more information on Tribuss/Atroiza here:
    http://i-base.info/guides/1561

    And on resistance here:
    http://i-base.info/guides/changing/how-do-missed-doses-lead-to-resistance

  9. Conny

    Hi i was using tribuss but i ran out of my treatment so my friend gave me atroiza can i take it

  10. Simon Collins

    Hi Santo

    Odimune and Atroiza contain the same active drugs. It is good you feel less sleepy now, but this may have also happened if you stayed on Odimune, as your body got used to the meds.

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