Q and A

Question

Please can you answer these three questions about CD4 count?

Please can you give me advice about these three situations?

Situation 1: I am last two years positive. age 33 man. i am not on medicine. my cd4 1515. viral load undetectable.
No smoking no drinking. Eat well. Can I live long?

Situation 2: I am fit and hiv+ my last cd4- 1200. no viral load. I am not on meds because i am afraid about ARVs.
what can i do? what is the right time to start ARVs? can I use a healthy diet to improve my CD4 count without using ARVs for 15-20 years?

Situation 3: My CD4 660 viral load 400. i am not on med. if my CD4 is over 500, does that mean i am normal as HIV negative person? I am slim so what can do to increase my weight?

Answer

Hi,

Thanks for your emails. Please see our Introduction to combination therapy for general information about CD4 counts, viral loads and starting treatment.

Situation 1

A CD4 count of 1515 is high but still in the normal range. The ‘normal’ range for HIV negative people is 400-1600, so you are right at the top of this. This suggests that your immune system has not been damaged by HIV. It is very unusual to have an undetectable viral load when you are not on treatment. A very small number of people do have this, but it’s important to check with your doctor if this is correct.

If these test results are correct this means you are doing very well. You will need to be monitored regularly by a doctor. If your CD4 count drops you may need to start treatment with ARVs. In the UK people usually start treatment when thier CD4 coiunt is between 350 and 500. So long as you start treatment if/when you need it your life expectancy almost the same as an HIV negative person.

Situation 2

When you say you have ‘no viral load’ do you mean that you have been told this is undetectable, or that you do not have access to viral load testing?

A CD4 count of 1200 is very good. In most countries people don’t start ARVs until their CD4 count is below either 500 or 350.

Almost everybody needs treatment at some point but the time it takes between infection and your CD4 count dropping to 350 varies a lot between people. Please see this page about average time to treatment.

No foods, supplements or herbs can increase your CD4 count. ARVs are the only medicines that can do this. Eating a healthy diet may help to maintain your CD4 count for longer though and is good for your health generally.

Situation 3

Are you HIV positive? I have assumed that you are in answering this question, although you as if you are normal ‘as HIV negative person’.

A CD4 count of 660 is very good, and a viral load of 400 is also good. This shows that your immune system is still strong. Please see this page for information about CD4 counts and risk of illness.

If you want to gain weight you will need to increase the number of calories you eat. If you are worried that your weight is too low and you can not gain weight it’s important to discuss this with your doctor.

184 comments

  1. Roy Trevelion

    Hi Thutu,

    It’s good to hear you’ve started HIV meds. Modern HIV treatment (called ART) can reduce your HIV viral load by over 90% in the first days and weeks.

    However, CD4 counts take longer to recover. Please see this page in ART in Pictures that shows what happens as soon as we start treatment.

    You can ask your doctor if you need to take antibiotics while your CD4 count recovers. Antibiotics can help stop other infections if your CD4 count is low.

    Please let us know what HIV meds you’re taking.

  2. Thutu

    Hey
    I test hiv positive on 2018 and didn’t believe it and went to test again in 2020 sep and found out it was true,my CD4 COUNT is 77 and my viral load is high but I keep on gaining weight never got sick. My partner keeps on testing negative. So I want to know is it possible for my CD4 Count to increase in just 3 weeks after taking meds course they stopped me at work?

  3. Roy Trevelion

    Hi Alex,

    Your CD4 count is in the normal range for someone who is HIV negative. And the two results don’t look significantly different.

    But it’s great that you’ve started taking ARVs. HIV treatment (ART) starts to work from the very first pill. And viral load can drop by 90% within the first few days, and by 99% within the first few weeks. Please see this page from ART in Pictures. This shows what happens to viral load and CD4 counts after starting ART.

    But you can ask your doctor to test your viral load.

  4. Alexxe

    Hello,
    My CD4 is 666,but doctor not tested my viral load, i was first diagnosed HIV in may 2019, started ARV on may 2019.
    My first CD4 is 635 in july 2019, and last CD4 is 666, so what do you think can my viral load drop. In my first viral load it’s 2027 units.

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