Question
Do supplements interact with oral PrEP?
29 December 2022. Related: All topics, Drug interactions, PrEP.
Do the following supplements interact with prep?
– n-acetyl cysteine
– 5-htp L-5-hydroxytryptophan
– magnesium
– zinc
– Damiana extract
– Maca extract
– green tea extract (although is green tea fine to drink?)
– saffron
Thank you in advance for your brilliant service!
Answer
Hi there
Thanks for your Q and for the nice feedback.
The best reource for drug interactions with PrEP and other HIV meds is here:
hiv-druginteractions.org/checker
This is a comprehensive report of PrEP interactions with supplements. The few potential interactions, including green tea, are weak and/or unclear. None of the others in your list are a problem.
TD/FTC interactions other medications are covered here:
i-base.info/guides/prep/does-prep-interact-with-any-other-medications
These include some non-steroidal anti-inflammatory drugs (NSAIDs), especially diclofenac, ibuprofen and naproxen. Short-term use for a few days will be okay, but routinely taking both drugs together in the longer term can cause kidney problems.
best wishes
Simon
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