Q and A

Question

Why has my CD4 count dropped? What about cholesterol?

Hello

The other day I sent a question. You replied under a heading “My viral load has increased from undetectable to 87”.

As you suggested, I had a second time test immediately. The test results indicate that my CD4 count has come down from 284 to 195 c/ml, my CD4 % is 12 and my VL became less than 40 (undetectable) again.

Though my viral load is now back to undetectable, why has my CD4 count gone down so much in a matter of abount 3 weeks?

I also had my cholesterol tested and the result s 230. My HDL/LDL percentage 3.6 (which they say is in the average risk range). Could this cholesterol problem be a due to the the ARV medication (AZT, lamuvidine and efavrenz)?

Do I have to change treatment?

My doctor advises me not to take meat, milk and other faty foods, but are not these types of food necessary for recovering my CD4 count?

Answer

Thanks for letting us know your recent results.

It is good that the second test showed that your viral load had become undetectable again without any need to change treatment.

These low-level blips are very common, and confirming any unexpected results with a second test is always recommended.

In a similar way, the change in your CD4 count is likely to just be a natural fluctuation. CD4 results can fluctuate quite widely on a daily or weekly basis. It is more important on treatment that your viral load is undetectable.

Your CD4 is likely to be back to normal after your next test.

Information about lipids (cholesterol and triglycerides) are included at this link in the i-Base side effects guide.

Your HIV meds could easily be having an impact on your cholesterol and HDL:LDL ratio.

Taking more exercise and looking at diet changes are usually recommended first before considering changing treatment.

European guidelines (EACS) recommend the following summary:

Diet counselling:

2 comments

  1. Simon Collins

    Hi

    HIV treatment should work well for you. Your CD4 count is still good, but treatment will reduce the HIV in your body and your CD4 count should then become even higher.

    If you notice any side effects or changes in your moods then speak to your doctor in case this is related to the treatment.

    Otherwise, treatment should protect your health and help you live longer. IT is better that you are now on treatment.

    Perhaps also contact a local support group where you can talk to other people who are also HIV positive and who have gone through similar experiences.

  2. joice

    Hello I just found out that I’m HIV positive and my cd4 count is 195. Other results are good but I’m so scared. I’m fine, I have no pain or headache, I have started treatment. Am I gonna live longer?

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