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Featured HTB news: EHRC consultation on trans rights, US funding crisis, activists against Trump, using CAB-LA with lenacapavir, US guidelines on statins and PEP

Respond to the EHRC consultation, metabolic syndrome and INSTIs, US vaccine advisory replaced, Gates to fund lenacapavir PrEP, US funding crisis

RIO study

The RIO study was launched in 2021 to see whether immune-based therapy (called bNAbs) can be used instead of HIV treatment (ART). First results have just been presented at the CROI 2025 and BHIVA 2025 conferences. CROI 2025: RIO study: …

Slide sets from talks and workshops

Selected slide sets from around 100 community workshops and conference talks from the last 20 years. These are free to use for any non-commercial application. When third-party slides are used these remain the copyright of the original author. Ethical issues …

Featured Support i-Base: The Denver Principles – a new riso print by Jane Shepherd

A new print by Jane Shepherd to help raise funds for HIV i-Base.

Featured Reduced dosing: a possible crisis response to ART stockouts and closed clinics

Simon Collins, HIV i-Base An open access paper, fast-tracked in the journal AIDS, reviews seven studies that randomised almost 1300 participants to take ART on only 5, 4 or 3 days a week compared to daily dosing.  At week 48, …

PrEP – a pocket guide (2025)

Pocket PrEP is a introduction to how PrEP based on new changes to the UK BASHH 2024 guidelines (4-minute easy read). Download pocket PrEP – PDF (May 2025) More pocket ART pages Full guide to PrEP There is also a more …

PEPFAR news and links

This list of links and resources related to the US decision to cancel international aid covers January to March 2025. Selected latest news posted first. For updated news on the changing impact of US policy changes please see Global Health …

Practical facts about stopping ART if your clinic is closed: webinar on safety and risk

This community webinar includes practical information about stopping ART if your clinic is closed or has run out of HIV meds. This included a talk about the safety and risks of stopping ART in different situations. Are you worried about …

CHANGE: Community Health & HIV advocates navigating global emergencies

CHANGE website (documents, news, press statements etc) CHANGE stands for Community Health & HIV Advocate Navigating Global Emergencies. This is an international network of more than 1000 HIV advocates. It was launched in January 2025 after the first news about …

CROI 2025 in the shadow of Trump: reports include possible cure after bNAbs

9 to 12 March 2025, San Francisco Introduction Simon Collins, HIV i-Base This year’s CROI is being held from 9 to 12 March in San Francisco, California. [1] This will not be a normal CROI. This year the conference is …

PEPFAR crisis: US policy changes over global aid

Resources and links related to Trump cancelling international committments, including HIV and TB treatment and prevention

Mpox: Q&A factsheet

Factsheet on mpox (monkeypox): prevention, treatment, vaccines…

UK guide to PrEP (February 2025)

2025 guide to PrEP: start with a double dose and new event-based options for all

capsid inhibitor (CI)

capsid inhibitor – this is a new type of HIV drug that works at several different stages of the HIV lifecycle. Lenacapavir is currently to only approved capsid inhibitor. The long-acting HIV med only needs to be given by subcutaneous …

Introduction to ART (November 2024)

This widely used guide to HIV treatment (ART) has been updated online.

obstetrics

obstetrics – a branch of medicine that refers to the care of women during pregnancy.

Lactation

lactation – the process of producing and releasing milk from the mammary glands in your breasts. Lactation begins in pregnancy when hormonal changes signal the mammary glands to make milk in preparation for the birth of your baby.

Hepatitis C for people living with HIV (November 2024)

What is hepatitis C? Testing, diagnosis and monitoring. New treatment and drugs in development. Deciding whether to treat or wait. Sexual transmission and safer HCV sex.

U=U: Undetectable = Untransmittable

U=U: Undetectable viral load = Untransmittable HIV. Has your doctor talked to you yet?

DAA (direct acting antiviral)

DAA (direct acting antiviral) – new hepatitis C drugs that work directly against the hepatitis C virus (HCV). The following links are to UK prescribing information for DAA combinations plus ribavirin. Elbasvir/grazoprevir https://bnf.nice.org.uk/drugs/elbasvir-with-grazoprevir/ Sofosbuvir/ledipasvir https://bnf.nice.org.uk/drugs/ledipasvir-with-sofosbuvir/ Glecaprevir/pibrentasvir https://bnf.nice.org.uk/drugs/glecaprevir-with-pibrentasvir/ Sofosbuvir/velpatasvir  https://bnf.nice.org.uk/drugs/sofosbuvir-with-velpatasvir/ Sofosbuvir/velpatasvir/voxilaprevir https://bnf.nice.org.uk/drugs/sofosbuvir-with-velpatasvir-and-voxilaprevir/ Ribavirin (RBV) …

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