September 2001

Contents

Conference reports

• 1st IAS Conference on HIV Pathogenesis and Treatment, July 8-11 2001, Buenos Aires, Argentina

• Lipodystrophy and metabolic complications

• Lipodystrophy and metabolic disturbances

• Pharmacology at 1st IAS

• Drug-drug interactions

• Entry inhibitor updates from the 1st IAS

• Structured treatment interruptions (STIs) and structured intermittent therapy (SITs)

• Adverse events with antiretrovirals

Antiretrovirals

• Durable HIV treatment benefit despite low-level viraemia: reassessing definitions of success or failure

• Anticancer drug 9-nitrocamptothecin (9NC) inhibits HIV-1 replication

Treatment strategies

• Immunotherapy at the 1st IAS conference

Treatment access

• Drug companies’ spending on advertising double research and development spending in 2000

• Nigeria to launch AIDS treatment program

Guidelines

• Updated US Public Health Service guidelines for the management of occupational exposures to HBV, HCV and HIV and recommendations for postexposure prophylaxis (PEP)

Side effects

• Carnitine for high triglycerides

• Does efavirenz cause breast enlargement?

• Fat malabsorption common cause of diarrhoea in HIV-positive patients

• Dietary supplements can help with nelfinavir-related diarrhoea

• HCV coinfection may have role in changes in body composition in HIV patients

Coinfections and complications

• Interferon shows some benefit in preventing AIDS-related opportunistic infections

Vaccines and microbicides

• Trials of Immune Response Corp’s AIDS vaccine Remune may end after Pfizer drops financial support

Other news

• Europe moves to speed up approval of new drugs

• Deal allows developing countries free access to journals

On the web

• AIDS research today: 20 views

PDFs

• Volume 2 Number 7 August/September 2001 PDF