March 2006

Contents

Conference reports

• 13th Conference on Retroviruses and Opportunistic Infections (CROI), 5-8 February 2006, Denver

• Early integrase inhibitor studies in treatment experienced patients raise hopes for new drugs in a new class

• Atazanavir in treatment naive patients, with and without ritonavir boosting

• Simplification to atazanavir/ritonavir monotherapy

• Summary of STI studies: SMART shows clear increased risk from interrupting treatment at any CD4 count

• The effect of repeated single-dose nevirapine for PMTCT in a second pregnancy

• Should criteria for initiation of HAART be revisited in pregnant women?

• Cotrimoxazole prophylaxis in pregnancy

• Treatment in primary HIV infection

• CNS penetration of ARV drugs is associated with lower CSF viral load

• Sexual transmission of hepatitis C in HIV-positive men in the UK

• D:A:D study shows that PIs rather than NNRTIs drive the previously reported cardiovascular risk of combination antiretroviral therapy

• Interventions for the management of lipodystrophy and metabolic complications

• 45th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 16-19 December 2005, Washington, USA

• One third of HIV/HCV coinfected patients with normal ALT have advanced fibrosis in Spanish cohort

Antiretrovirals

• Metrex formulation of Kaletra available on named patient access in UK

• Treatment-naive trial of tipranavir discontinues highest dose arm

Treatment strategies

• Therapeutic vaccinations and treatment interruptions

Treatment access

• TAC wins court case against Matthias Rath

• BMS licenses atazanavir to generic drug companies

Guidelines

• UK guidelines on PEP after sexual exposure (March 2006)

Other news

• New US prescription drug information format to improve safety

On the web

• 2nd International workshop on HIV and Hepatitis coinfection

• Medscape training resources

• HIV InSite Knowledge Base

• Top 10 research publications in HIV care in 2005

• Cardiovascular risk factors and metabolic complications in HIV-positive patients receiving HAART

• Report on dispersal of asylum seekers in the UK

• UK surveillance report

• GMHC: Treatment Issues

• FCHR roundtable report on CCR5 inhibitors

• IAVI report: 2005 year in review

• WHO – HIV/AIDS in Europe: moving from death sentence to chronic disease management

• Full text journal publications online

PDFs

• Volume 7 Number 3 March 2006 PDF